Role of Fine Needle Aspiration Cytology in the Assessment of Intra-Abdominal and Retroperitoneal Lesions-A Comparative Study
Journal Title: National Journal of Laboratory Medicine - Year 2016, Vol 5, Issue 3
Abstract
Introduction: Fine needle aspiration cytology (FNAC) is a widely used valuable, accurate, and safe method which was initially applied only for readily palpable masses.But in recent years previously inaccessible lesions and deeper organs are safely aspirated using the fine needle under radiological guidance. Aim: This study was conducted to evaluate and confirm the diagnostic utility of FNAC in intra-abdominal and retroperitoneal lesions. Materials and Methods: This study was conducted on 660 patients with clinically suspected intra-abdominal and retroperitoneal lesions. Ultrasound guided (USG) or computed tomography (CT) guided FNACs were performed and the smears stained with Haematoxylin and eosin (H and E) and May Grunwald Giemsa (MGG) stains. A cyto-histopathological correlation was done where ever possible. Results: Among the 660 patients studied, 65% were CT guided FNACs and 35% were USG guided. A cytopathological diagnosis was obtained in 477 cases (72%) of which 135(28.3%) werenon malignant (benign neoplasms and non neoplastic) lesions and 342 (71.7%) were malignant lesions. Liver was the most frequently aspirated organ. Pyogenic abscess of the liver and hepatic metastasis were the commonest non malignant and malignant lesions respectively. With the available cytohistopathological correlation, the overall accuracy was 85%, the sensitivity for true positive results was 83%, the sensitivity for true negative results was 88%, the positive predictive value (PPV) was 94% and the negative predictive value (NPV) was 68%. No major complications were observed. Conclusion: Guided FNAC was thus confirmed as a safe procedure that provides fairly accurate diagnosis with minimal complications in the diagnosis of intra-abdominal and retroperitoneal lesions.
Authors and Affiliations
Dr. Aparna Amogh Naik Namshiker, Dr. Premila De Sousa Rocha, Dr. Roque G. W. Pinto
Keywords
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- EP ID EP380169
- DOI 10.7860/NJLM/2016/18812.2139
- Views 111
- Downloads 0
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