Role of high sensitive C–reactive protein in asthma patients
Journal Title: IOSR Journal of Biotechnology and Biochemistry (IOSR-JBB - Year 2019, Vol 5, Issue 1
Abstract
Asthma is a clinical condition characterized by inflammation of the airways and C-reactive protein is a marker for inflammation, infection, tissue damage and host defence mechanism by complement pathway. Impaired respiratory functions are associated with disturbance in immune response in the lung. This immune response is characterized by the secretion of some inflammatory cytokines such as C-reactive protein and IL-6. The case-control study was conducted in the department of Biochemistry, People’s College of Medical Science & Research Centre Bhopal (M.P.). Total 200 subjects were selected for the study. The level of hs-CRP was measured using the nephelometric method. The mean value of serum high sensitive C-reactive protein was 4.74±2.24 in asthmatic cases and 2.53±1.31 in control group and p-value is ≤0.0001 which shows that serum hs-CRP was highly significant in asthmatic cases in comparison to the control group. It has been shown that serum level of hs-CRP in asthmatic patients were elevated compared with healthy controls and statistically highly significant difference was found. The overall finding shows that the High sensitive C-reactive protein is a marker for inflammation in asthma.
Authors and Affiliations
Pallavi Mishra, Dr. Prashant Hisalkar, Dr. Neerja Mallick
Keywords
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- EP ID EP443091
- DOI 10.9790/264X-0501010709.
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