ROLE OF MAST CELLS IN LEPROSY- A STUDY OF 62 CASES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 75
Abstract
BACKGROUND Mast cells have received little attention in leprosy, but evidence linking them with delayed-type hypersensitivity reactions raises the possibility that they may be of some importance in leprosy. MATERIALS AND METHODS The present study is a descriptive study. Biopsies obtained from the clinically diagnosed patients were fixed in 10% formalin, processed and three sections of 6 µm thickness were cut and stained with routine Haematoxylin and Eosin (Culling, Allison, Barr 1985), by Toluidine Blue and by Modified Thionin/Acridine Orange method. RESULTS Mean number of mast cells were more in lepromatous leprosy than in tuberculoid. CONCLUSION This study reflects the variety of immunological reactions occurring in leprosy and the role of mast cells in these immunological phenomena.
Authors and Affiliations
Shivani Jindal, Mridu Manjari, Monika Girdhar
Keywords
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- EP ID EP266566
- DOI 10.14260/Jemds/2017/1157
- Views 79
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