Role of PET/CT in Assessment of Colorectal Carcinoma
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 72, Issue 11
Abstract
<strong>Background:</strong> colorectal cancer is the second most common cause of cancer in women (9.2% of diagnoses) and the third most common in men (10.0%), it is the fourth most common cause of cancer death after lung, stomach, and liver cancer.<strong> Aim of the Work:</strong> the goal of this study was to elucidate the role of 18F-FDG PET-CT in evaluation of colorectal cancer.<strong> Patients and Methods:</strong> twenty five patients with histopathologically proven colorectal primary malignancy were evaluated for suspected local recurrence and metastasis. No age predilection and both sexes were included, clinical history, image follow-up, tumor markers, and pathological reports were reviewed for gold standard.<strong> Results:</strong> the final diagnosis of distant metastasis and/or local recurrence in post-therapeutic cancer colon was evident in 70% of our patient population with PET/CT sensitivity of 95.6%, specificity of 91.4%, (NPV) of 88.9%, (PPV) of 96.7%, and diagnostic efficacy of 94.4% and CT sensitivity of 62.6%, specificity of 48.6, (NPV) of 33.3% (PPV) of 76.0%, and diagnostic efficacy of 58%.<strong> Conclusion:</strong> PET/CT is a better method to evaluate post-therapeutic colorectal cancer patients.
Authors and Affiliations
Eman Helal
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