Role of Platelet Indices in Various Causes of Thrombocytopenia: A Tertiary Care Hospital Study
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 8
Abstract
Abstract Introduction:- Platelet indices (PI) — plateletcrit (PCT), mean platelet volume (MPV) and platelet distribution width (PDW) — are a group of derived platelet parameters obtained as a part of the automatic complete blood count. Emerging evidence suggests that PI may have diagnostic and prognostic value in certain diseases. This study aimed to summarize the current scientific knowledge on the potential role of PI as a diagnostic tool in patients having thrombocytopenia. Objectives: To study variations in platelet parameters in relation to the cause of thrombocytopenia Materials and methods: This cross sectional study was carried out in the Pathology department of a teaching tertiary care hospital, after obtaining Institute Ethics committee clearance. Patients admitted with thrombocytopenia were enrolled in the study. This study spanned over 2 years. A total of 319 cases were studied. Conclusion: Thrombocytopenia remains one of the commonly encountered abnormalities in clinical situations. Identification of cause of thrombocytopenia is crucial in patient management. Platelet parameters (MPV, PCT, PDW) assessed according to patho-physiological mechanisms were not significantly different. Of the three parameters, alteration in PCT was found to have statistical significance, in patients of thrombocytopenia.
Authors and Affiliations
Dr. Anne Wilkinson
Keywords
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