ROLE OF PLEURAL BIOPSY IN THE EVALUATION OF UNDIAGNOSED EXUDATIVE PLEURAL EFFUSION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 65
Abstract
BACKGROUND Determining the cause of a pleural effusion is greatly facilitated by analysis of the pleural fluid. Many pleural effusions remain undiagnosed after routine tests of pleural fluid. So, we need a simple and safe investigative tool to evaluate such undiagnosed pleural effusions. MATERIALS AND METHODS Patients with undiagnosed exudative pleural effusion after pleural fluid analysis were subjected to pleural biopsy using Abram’s pleural biopsy needle under local anaesthesia and the specimen was sent, histopathological examination, reverse transcriptase polymerase chain reaction for tuberculosis and culture for tuberculosis by BACTEC. RESULTS About 78.5% of cases were diagnosed when combining histopathological examination, BACTEC culture and reverse transcriptase polymerase chain reaction on pleural biopsy specimen. CONCLUSION Closed pleural biopsy can be used as an easy, quick, cost effective and relatively safe method to diagnose an exudative effusion not diagnosed by pleural fluid analysis. Combination of histopathological examination, BACTEC culture and reverse transcriptase polymerase chain reaction in closed pleural biopsy has a greater diagnostic yield in diagnosing exudative effusions not diagnosed by pleural fluid analysis.
Authors and Affiliations
Bharathibabu K, Elamparithi S, Saravanavasan R
Keywords
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- EP ID EP231693
- DOI 10.14260/Jemds/2017/1023
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