Role of Post Mastectomy Radiotherapy in T1,T2 Lesions with 1-3 Positive Axillary LymphNodes - A Retrospective Study of 101 Cases.
Journal Title: Gujarat Medical Journal - Year 2019, Vol 74, Issue 1
Abstract
Postmastectomy radiation (PMRT) has been shown in multiple randomized trials to reduce locoregional recurrence (LRR) rates and improve survival in women with locally advanced breast cancer.1There is international consens us to recommend PMRT for patients with tumour size more than 5 cm (T3), tumour invasion of the skin, pectoralmuscle or chestwall (T4) and patients with > 4 positive lymphnodes (LN) . The role of PMRT in patients with early-stage T1-2 disease with limited nodal metastasis remains a subject of ongoing debate.2 Controversy surrounding the optimal locoregional management of the subset with one to three positive nodes stems from conflicting data on the benefits of PMRT in this population. The side effects of radiotherapy and it sassociated morbidity have to be considered in the risk benefit ratio, thus difficult to arrive at consensus in early breast cancer.3This study reports the findings from use of post operative RT (radiotherapy) on such less afflicted patients at tertiary regional cancer centre in India
Authors and Affiliations
Rajan A Tankshali, Nikhil Garg, Manish Sadhwani
Keywords
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