Role of Rectal Misoprostol Versus Intramuscular Oxytocin In The Active Management Of Third Stage Of Labour.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Objectives: Atonic postpartum hemorrhage accounts for 80% of cases of postpartum hemorrhage and active management of third stage of labour has become a central component of postpartum hemorrhage reduction strategies. This study is conducted To assess and compare the blood loss at delivery between the rectal misoprostol and intramuscular oxytocin groups. To evaluate the change in haemoglobin levels in each group. To estimate the incidence of adverse effects of rectal misoprostol and intramuscular oxytocin groups. Materials And Methods: This study was a prospective non randomized controlled study in which 100 primigravida at term who had vaginal delivery were divided into two groups. Rectal Misoprostol (600 mcg) versus intramuscular Oxytocin(10 international units) at the time of delivery of anterior shoulder . Blood loss was estimated, Haemoglobin and PCV levels were estimated pre and post delivery. Results: Mean blood loss was 175 ml in misoprostol group 212 ml in oxytocin group. There was a mean difference of 1.08 g/dl and 1.24 g/dl between predelivery and postdelivery haemoglobin levels noted in misoprostol and oxytocin groups respectively. Conclusions: Administration of rectal misoprostol is as effective as intramuscular oxytocin in terms of reduction in haemoglobin concentration and PCV 24 hours after delivery when compared to predelivery levels. Misoprostol offers the advantage of administration by unskilled health workers and is thermostable and cheap and hence can be used in poor resourse settings.
Authors and Affiliations
Dr P Supriya, Dr B Sandhya
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