ROLE OF TELOMERES IN CAUSING CANCER AND TARGETING TELOMERASE IN TREATMENT OF CANCER AS BETTER THAN CONVENTIONAL THERAPY
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2015, Vol 6, Issue 2
Abstract
Telomere that is a part of chromosome can play a vital role in causing cancer in human beings by targeting that part the treatment becomes easy and majority of the investigations are showing that the activation/expression of hTERT in body is the main cause for the carcinoma condition that occurred in the patient. It has discussed about the percentage of cancer cases that has diagnosed with carcinoma condition occurred due to the expression of hTERT and also discussed about the therapies can be given are that can be used to target the telomeres to treat carcinomic stages in cancer patients.
Authors and Affiliations
Poitha M, Lavakumar V, Ashok Kumar C. Koj
SYNTHESIS, CHARACTERIZATION AND PHARMACOLOGICAL EVALUATION OF STRUCTURALLY RELATED COMPOUNDS OF DIBENZOXEPIN AND DIBENZOTHIEPIN
This study was designed to synthesize, characterize and to evaluate the pharmacological activity of Dibenzoxepin and Dibenzothiepin derivatives. Totally three compounds, two Dibenzoxepin derivatives and one Dibenzothiepi...
ANTISENSE TECHNIQUE TO TREAT BREAST CANCER – A REVIEW
There are many genes which are responsible for developing breast cancer especially, BRCA2 (Breast Cancer 2) and HER2 are extensively involved in developing breast cancer and hence it is the centre of attractions for all...
EFFECTS OF AGEING ON LEVELS OF NT-PROBNP [AMINO TERMINAL-PRO BRAIN NATRIURETIC PEPTIDES] IN ELDERLY DIABETES MELLITUS TYPE-II FEMALES
To investigate the serum NT-proBNP, as a biomarker of cardiovascular diseases-Left ventricular hypertrophy, in females with diabetes type-II and its association with conventional cardiovascular risk factors i.e., Total...
IN VITRO STUDY OF ENTAMOEBA HISTOLYTICA CAUSATIVE AGENT OF AMOEBIASIS WITH LEMON JUICE AT DIFFERENT CONCENTRATION SHOWED ANTIAMOEBIC PROPERTIES
A species of parasite protozoa Entamoeba histolytica causing amoebiasis and amoebic dysentery characteristic include a single nucleus containing a small central karyosome and peripheral chromatin that is finely and regul...
NOVEL 3-ACETYLCOUMARIN SCHIFF’S BASE SYNTHESIS FROM DIFFERENT ACID HYDRAZIDE
A new series of Schiff’s bases, SB1, SB2 and SB3 were synthesized from 3-acetylcoumarin and different acid hydrazides. The 3-acetyl coumarin was synthesized starting from salicylaldehyde and ethylacetoacetate. The struct...