ROLE OF TOPICAL APPLICATION OF SHRINGVERADI EYE DROPS IN NETRABHISYANDA WITH SPECIAL REFERENCE TO ALLERGIC CONJUNCTIVITIS
Journal Title: Journal of Biological and Scientific Opinion - Year 2015, Vol 3, Issue 4
Abstract
Ocular allergy manifests as a number of distinct disease entities, ranging from allergic conjunctivitis, a relatively mild condition, to keratoconjunctivitis, which may be sight-threatening condition affecting the cornea. Underlying immune mechanism behind this has not yet been fully understood, but it is known that IgE related mast cell and eosinophil mediated inflammation leads to the release of mast cell mediators and toxic eosinophil granule protein and enzymes. Patients suffering from ocular allergy might experience such symptoms such as redness, itching, burning, swelling or dryness in eyes in differing degrees of severity and duration. Based on clinical features Allergic conjunctivitis can be correlated with Abhisyanda of predominantly a Kaphaja etiology. The features like itching, edema of conjunctiva and lid, heaviness of eyelid indicate Kaphaja etiology of allergic conjunctivitis. Features like burning sensation indicate vitiation of Pitta. Dryness of eye indicates vitiation of Vata. Redness suggests vitiation of Rakta. Hence, features of allergic conjunctivitis are mainly linked with Kaphaja activity with subsidiary action of other doshas .To search a safe, potent and cost-effective Ayurvedic treatment for Netrabhisyanda a randomized control clinical trial was conducted on 67 patients. Patients were divided in three groups 25 in Group I (Control Group i.e. Ketotifen 0.025%), 27 in group II (trial Group i.e. Shringveradi Drops) and 15 in Group II I (Placebo i.e. Normal saline) treated topically four times per day for 14days.The effect of Ayurvedic management was found to be equivalent to the standard therapy and more effective than placebo, although the trial drug showed more effect in blepharitis and follicles in lower palpebral conjunctiva. Study shows that Shringveradi eye drops can be used as potent, safe and cost-effective treatment to ameliorate the symptoms of allergic conjunctivitis.
Authors and Affiliations
Sakshi Kanaujia , Manoj Kumar
Keywords
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- EP ID EP133121
- DOI 10.7897/2321-6328.03437
- Views 93
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