Rubella and cytomegalovirus seroprevalance among pregnant women admitted to Ege University Hospital
Journal Title: Ege Tıp Dergisi - Year 2014, Vol 53, Issue 4
Abstract
Aim: Primary infections caused by rubella and cytomegalovirus (CMV) can lead to serious complications in pregnancy. The purpose of this study was to determine seroprevalences of the rubella virus and CMV retrospectively, from samples from pregnant women which were sent to the Ege University Hospital Medical Microbiology Laboratory. Materials and Methods: Between January 2011 and December 2011, 1875 pregnant women (age range 14-57, mean 29.5 years) were screened for rubella antibodies and 1847 pregnant women (age range 17-45, mean 29 years) were screened for CMV antibodies. Serum samples were tested by the automated commercial ELISA system. Results: Rubella IgG seropositivity was detected in 1744 (93.2%) and rubella IgM was detected in 3 (0.2%) of the 1875 pregnant women. For CMV, IgG seropositivity was found in1339 (99%) and CMV IgM in 25 (1.4%) of the 1847 pregnant women. A statistically significant reduction in rubella IgG levels with an increase in age was recorded (p=0.006). Conclusion: The problems that can be caused by primary CMV and rubella infections during pregnancy are serious. For prevention of rubella infections, vaccination programs should be carried out carefully. For CMV infection prevention in pregnancy, determination of the status of CMV immunity before pregnancy and informing pregnant women about preventive measures for transmission of CMV are extremely important.
Authors and Affiliations
F K Varıcı Balcı, A Arslan, R Sertöz, İ Altuğlu
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