Safety and Diagnostic Accuracy of Dobutamine Stress Echocardiography
Journal Title: Nepalese Heart Journal - Year 2009, Vol 6, Issue 1
Abstract
Exercise and pharmacologic stress echocardiography has been used routinely in clinical practice for the past twenty to thirty years. Dobutamine stress echocardiography (DSE) is well established as a safe, feasible, and accurate modality for detection of myocardial ischemia and prognostication in patients with known or suspected coronary artery disease, particularly when they have limited exercise capacity. Serious side effects during or shortly after DSE are uncommon, with ventricular fbrillation or myocardial infarction occurring in approximately 1 of 2,000 studies. No deaths have been reported. On the basis of a total number of 2,246 patients, reported in 28 studies, the sensitivity, specifcity and accuracy of the test for the detection of coronary artery disease (CAD) were 80%, 84% and 81%, respectively. Mean sensitivities for one, two and three-vessel disease were 74%, 86% and 92%, respectively. The sensitivity of detection of disease in the let circumflex coronary artery (55%) was lower, both compared with that for left anterior descending (72%) and right coronary artery disease (76%). The sensitivity of predicting multivessel disease by multiregional echocardiographic abnormalities varied widely, from 8% to 71%. In direct comparisons, DSE was superior to exercise electrocardiography and dipyridamole echocardiography and comparable to exercise echocardiography and radionuclide imaging. DSE is useful, feasible and safe exercise independent stress modality for assessing the presence, localization and extent of CAD.
Authors and Affiliations
Shah RK| Department of Cardiology, NAMS, Bir Hospital, Kathmandu, Nepal
Keywords
Related Articles
- EP ID EP15673
- DOI http://dx.doi.org/10.3126/njh.v6i1.18599
- Views 491
- Downloads 26
"How I do it" Aortic Valve Replacement in case of Double Valve Replacement
Echocardiographic Profile of Patients in Dhulikhel Hospital, A Medical College Hospital in Nepal
Background and Aim : Echocardiograph is an important diagnostic tool to evaluate cardiac disease and is indispensible for management. So it is important to know the spectrum of cardiac abnormalities that can be detect...
Multivessel primary PCI in patient with peripheral arterial disease
Thrombosis of multiple coronary arteries is extremely rare fnding in the setting of acute myocardial infarction. This often leads to cardiogenic shock and sudden cardiac death. We report a case of 61 years old gentleman...
Awareness and Practice of Prevention of Myocardial Infarction among Hypertensive Patients: Cross Sectional Study in a Tertiary Cardiac Centre of Nepal
Background and Aims: Hypertension is one of the emerging public health problems in developing country like Nepal. Among complications of hypertension, Myocardial Infarction is most distressing. Although, myocardial inf...
Acute Myocardial Infarction in Young Adults: Study of Risk factors, Angiographic Features and Clinical Outcome
background and aims: Acute myocardial infarction below 45 years of age constitutes a specifc subset of population having different risk factors and clinical features as compared to older patients. Pattern of coronary...