Safety and Effectiveness of Anti-Retroviral Drug Regimens Zln and Tle in Tertiary Care Teaching Hospital: A Prospective Observational Study.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 2
Abstract
There is no cure for HIV, but there are treatments to enable most people with the virus to live a long and healthy life. AIDS is the final stage of HIV infection, when your body can no longer fight life-threatening infections. With early diagnosis and effective treatment, most people with HIV will not go on to develop AIDS. present study shows, In low resource settings, fixed-dose combinations of nucleoside reverse transcriptase inhibitors (NRTIs) such as Tenofovir and Lamivudine; and non-nucleoside reverse transcriptase inhibitors (NNRTIs) such as Efavirenz, are commonly used as Antiretroviral therapy for HIV-infected patients in order to increase adherence to lifelong treatment. The purpose of the study is to determine the Safety and Efficacy of Anti-Retroviral Drug Regimens ZLN (Zidovudine+Lamivudine+Nevirapine) And TLE (Tenofovir+Lamivudine+Efavirenz) in Tertiary Care Teaching Hospital. From the study both ZLN and TLE regimens for treatment in HIV patients are efficacious in improving both CD4 count (p value: 0.016). Now even though the combination of ZLN is very efficacious as a anti retroviral drug regimen, but TLE should be preferred by the physicians in Govt.general hospital.
Authors and Affiliations
Hemasri M1, Dr. Sudhapoornima P, Sowmya Sri CH, Ramya S, Avinash I, Kiran Kumar B
Keywords
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