Safety and Effectiveness of Anti-Retroviral Drug Regimens Zln and Tle in Tertiary Care Teaching Hospital: A Prospective Observational Study.

Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 2

Abstract

There is no cure for HIV, but there are treatments to enable most people with the virus to live a long and healthy life. AIDS is the final stage of HIV infection, when your body can no longer fight life-threatening infections. With early diagnosis and effective treatment, most people with HIV will not go on to develop AIDS. present study shows, In low resource settings, fixed-dose combinations of nucleoside reverse transcriptase inhibitors (NRTIs) such as Tenofovir and Lamivudine; and non-nucleoside reverse transcriptase inhibitors (NNRTIs) such as Efavirenz, are commonly used as Antiretroviral therapy for HIV-infected patients in order to increase adherence to lifelong treatment. The purpose of the study is to determine the Safety and Efficacy of Anti-Retroviral Drug Regimens ZLN (Zidovudine+Lamivudine+Nevirapine) And TLE (Tenofovir+Lamivudine+Efavirenz) in Tertiary Care Teaching Hospital. From the study both ZLN and TLE regimens for treatment in HIV patients are efficacious in improving both CD4 count (p value: 0.016). Now even though the combination of ZLN is very efficacious as a anti retroviral drug regimen, but TLE should be preferred by the physicians in Govt.general hospital.

Authors and Affiliations

Hemasri M1, Dr. Sudhapoornima P, Sowmya Sri CH, Ramya S, Avinash I, Kiran Kumar B

Keywords

Related Articles

Adsorption Efficiency versus Swelling Rates Of Chit

The presence of synthetic textile dyes in aqueous effluents, out streamed by industries causes terrible environmental pollution. Most of the synthetic textile dyes are recalcitrant, poisonous and degradation resistant, h...

Genotypic Distinctions of Variability of Biochemical Composition of Fruits of Vacciniaceae Species under Conditions of Belarus

Result of research of quantitative characteristics of biochemical composition of fruits of 30 taxons of 3 Vacciniaceae species (such as V. covilleanum Butkus et Plishka (highbush blueberry), V. vitis-idaea L. (lingonberr...

Development and Validation of A RP-HPLC Method For Estimation of Flunitrazepam In A Tablet Dosage Form

A simple, sensitive, and precise high performance liquid chromatographic method for the analysis of Flunitrazepamhas been developed and validated for the determination of compound in commercial pharmaceutical products. T...

Evaluation of Serum Lactate as Predictor of Morbidity and Mortality in Sepsis and Trauma Cases

Background and objectives:Utility of serial serum lactate measurement to find patients in occult hypotension and its use in treating critically ill patients. Design:Prospective non interventional observation study in RGG...

Effect of Aqueous Extract of Defatted Flaxseeds (Linum Usitatissimum Linn) on Fructose-Induced Hypertension in Rats by Inhibiting Angiotensin-Converting Enzyme (ACE)

Linum usitatissimum Linn. is a widely acclaimed medicinal plant used in every household. The seeds of L. usitatissimum have both medicinal and nutraceutical properties.The study was conducted to evaluate the anti-hyperte...

Download PDF file
  • EP ID EP383447
  • DOI 10.9790/3008-1102018896
  • Views 88
  • Downloads 0

How To Cite

Hemasri M1, Dr. Sudhapoornima P, Sowmya Sri CH, Ramya S, Avinash I, Kiran Kumar B (2016). Safety and Effectiveness of Anti-Retroviral Drug Regimens Zln and Tle in Tertiary Care Teaching Hospital: A Prospective Observational Study.. IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS), 11(2), 88-96. https://europub.co.uk./articles/-A-383447