Safety and efficacy of intralesional MMR vaccine along with oral zinc in cutaneous warts
Journal Title: Medpulse International Journal of Medicine - Year 2017, Vol 4, Issue 2
Abstract
Background: Warts are one of the most common viral infections of humans in which the most frequently used modalities of treatment involve destruction of the affected area, which does not prevent recurrences and often results in scarring and not possible in multiple concept of immunotherapy for this condition. immunomodulator i.e. oral zinc and intralesional MMR vaccine for the Methods: This double blind randomized controlled clinical trial was conducted in department of dermatology at saraswathi institute of medical college, Hapur on 50 patients with warts who were allocated to two grou MMR group with oral zinc and normal saline group. MMR vaccine was injected intralesionally along with oral zinc in the first group, whereas normal saline was injected into the lesions in the second group. These injections were repeated every 2 weeks intervals for maximum 3 injections. All patients were followed up every 15day interval up to 45 days and then up to 6 months regarding relapses and finally, side effects, probable relapse, and therapeutic outcomes were evaluated and compared. Result complete cure in 80% cases, relative included complete cure in 4% cases, relative cure in 16% complication occurred in the two groups. wart is slightly better than used individually and is equally safe.
Authors and Affiliations
Sachin Agarwal, Prashant Kumar Yadav, Amarjeet Singh Verma, Harmeet Kaur
Keywords
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