Safety and efficacy of liposomal doxorubicin in a patient treated for metastatic breast cancer
Journal Title: OncoReview - Year 2015, Vol 5, Issue 4
Abstract
Breast cancer is the most common malignancy among women in Poland and all over the world. Despite the development of modern therapies, cytostatics still play one of the main roles in treatment of this disease. Classic anthracyclines, besides unquestionable efficacy in this disease, have a disadvantageous toxicity profile. Therefore, until now, there has been a limitation in using these drugs in patients with cardiological conditions and in patients who had previously taken anthracyclines. That was the cause for the development of a less toxic form of drug, which is liposomal doxorubicin – being as effective as classic anthracycline it has reduced cardiotoxicity. This article presents the case of a patient with metastatic breast cancer, in whom, after treatment with classic doxorubicin, liposomal form was administered which caused regression of liver metastases. Moreover, during treatment with liposomal doxorubicin, there has been no evidence of heart impairment.
Authors and Affiliations
Justyna Borucka
Keywords
Related Articles
- EP ID EP78726
- DOI 10.5604/20828691.1189724
- Views 200
- Downloads 0
Treatment of multiple superficial basal cell carcinomas with topical imiquimod
Basal cell carcinoma is the most common malignancy of man. The use of the topical imiquimod 5% cream offers a noninvasive, nonsurgical, and an effective option for the treatment of primary types superficial basal cell ca...
Limfohistiocytoza hemofagocytowa (HLH) indukowana przez chłoniaka – opis przypadku
Limfohistiocytoza hemofagocytowa (HLH) to rzadki (zwłaszcza u dorosłych) zespół objawów, w którym hiperzapalenie powoduje gorączkę, hepatosplenomegalię, pancytopenię i bez leczenia prowadzi do zgonu. Wśród wyników badań...
Superior efficacy of nilotinib vs imatinib in patients with chronic myeloid leukemia in chronic phase. ENESTnd and ENESTcmr current results analysis
Second generation tyrosine kinase inhibitors can improve the efficacy of treatment and outcome in newly diagnosed patients with chronic myeloid leukemia in chronic phase. The primary endpoint of ENESTnd trial is the comp...
Adjuvant imatinib after resection of gastrointestinal stromal tumour - systematic review and meta-analysis
[b]Background:[/b] Adjuvant therapy is recommended for population of patients with high risk of recurrence after resection of gastrointestinal stromal tumour.[b]The aim of the study:[/b] Evaluation of clinical efficacy a...
Satisfaction with life and health-promoting behaviours in the context of prevention and early detection of breast cancer in physically active women
Objective: Assessment of the impact of life satisfaction in physically active women on their health-promoting behaviours in terms of prevention and early detection of breast cancer. Materials and methods: The study, invo...