Salivary Alkaline Phosphatase- A Risk Indicator in Hemodialysis Patients with Chronic Periodontitis
Journal Title: Journal of Contemporary Medicine and Dentistry - Year 2018, Vol 6, Issue 3
Abstract
bone destruction and ultimately tooth loss. Alkaline phosphatase (ALP) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules and is a marker of bone metabolism. Elevated total serum alkaline phosphatase (ALP) values have been associated with increased mortality in the hemodialysis patients and also in the general population. Methods: The study included 20 subjects, 10 in each group in the age group of 30-50 years. Group A comprised of 10 systemically healthy individuals with chronic periodontitis. Group B comprised of 10 hemodialysis dependent Chronic kidney disorders (CKD) patients with chronic periodontitis. Results: The present study showed a significant increase in Alkaline Phosphatase value in hemodialysis-dependent CKD patients with chronic periodontitis (Group B) compared to systemically healthy subjects with chronic periodontitis (p value<0.005). Conclusion: Alkaline phosphatase could be used as a diagnostic marker of periodontitis in hemodialysis-dependent CKD patients. However, ALP cannot be solely responsible for periodontitis in hemodialysis dependent CKD patients but it can be used as an additional aid in diagnosing periodontitis.
Authors and Affiliations
Sajna H. R. , Amitha Ramesh, Biju Thomas, Santhosh Shenoy
Keywords
Related Articles
- EP ID EP454512
- DOI -
- Views 116
- Downloads 0
The Knowledge of Lithuanian Dentists about Medical Emergencies and First Aid
Background: Medical emergencies can occur at any time in the dental practice, posing a direct threat to patient’s life. No information is available on the occurrence of, and dentists’ readiness for, medical emergencies i...
Effect of Exercise on Blood Pressure in Athletes and Untrained Individuals
Background: Physical exercise is known to increase heart rate and thus also causes proportionate changes in Blood Pressure. In the present study we tried to evaluate the changes occurring in Systolic Blood Pressure and D...
Wound Closure-Alternatives to Sutures
Suturing remains the gold standard of wound closure. The technique of wound closure by means of needle and thread emerged several thousand years ago. The introduction of both new surgical devices and reengineered existin...
Prevalence of Asymptomatic Bacteriuria in Pregnant Women in a Tertiary Care Hospital at Akola
Introduction: Females in reproductive age group are at an increased risk of Urinary tract infection (UTI). Physiological changes during pregnancy leads to increase in frequency of UTI in pregnant women. This study is car...
A Clinico–Epidemiological Study of Alopecia Areata in a Tertiary Care Hospital of Telangana
Background: Hair is found only in mammals its primary role was to serve as insulation and protection from unwanted agents. Hair performs no vital functions, whatsoever in man but the psychological functions of hair seem...