Schwannoma of the adrenal gland
Journal Title: Journal of Medical and Allied Sciences - Year 2014, Vol 4, Issue 2
Abstract
Visceral schwannomas are extremely rare and are usually discovered incidentally on USG/CT-Scan. Primary schwannomas of the adrenal gland are extremely uncommon. It has been theorized that they originate from Schwann cells that insulate the nerve fibers innervating the adrenal medulla. Histopathological examination coupled with immunohistochemistry provides the definitive diagnosis. A 55 year old normotensive female presented with pain in the right loin since 5 months. Her renal parameters were normal. Contrast enhanced computed tomography of abdomen showed a well delineated 6.5 x 5cms mass at upper pole of her right kidney. 24-hour urinary metanephrine was slightly elevated (3.07mg/24hrs). A decline in Serum cortisol levels was observed following a dexamethasone suppression test (18.89nmol/l). Histopathological examination revealed a spindle cell tumor. Immunohistochemistry showed strong and diffuse positive staining for S-100 with negative expression for CD-117, desmin, CD-34, HMB-45, synaptophysin, chromogranin, cytokeratin, and SMA. Ki- 67 index was 2%.A diagnosis of cellular schwannoma of adrenal gland was confirmed.
Authors and Affiliations
Anunayi Jeshtadi| Department of Pathology, Osmania Medical College, Hyderabad-500095, Telangana, India, Neelima Govada| Department of Pathology, Osmania Medical College, Hyderabad-500095, Telangana, India, Shrinivas B. Somalwar| Department of Pathology, Osmania Medical College, Hyderabad-500095, Telangana, India, Soumya Nagulapally| Department of Pathology, Osmania Medical College, Hyderabad-500095, Telangana, India
Keywords
Related Articles
- EP ID EP12714
- DOI -
- Views 382
- Downloads 26
Periocular anthropometric study among adult Bangladeshi Buddhist Chakma females
The dimensions of the human body are affected by geographical, racial, ethnic, gender and age factors. So, a normative data of periocular measurements based on above factors are indispensable to identify any ocular pat...
A study of percutaneous K wire fixation in supracondylar fracture of humerus (SCFH) in children
Supra-condylar fracture humerus is common in children. This fracture is often not treated on time, and even when it is, often the ideal treatment is not given. The complications are many if not managed by a specialist,...
Simultaneous detection of Hepatitis B virus and Hepatitis C virus in human plasma using Taq-man chemistry
Designing a rapid, reliable and sensitive assay, for detection of hepatitis B virus and Hepatitis C virus variants by real-time PCR, is challenging at best. A recent approach for quantifying the viral load using the s...
Trends in surgical site infections in general surgery at a tertiary hospital
Surgical site infections (SSI) are a preventable cause of hospital acquired infections, which increase morbidity and mortality. This is a retrospective analysis of SSIs in patients undergoing general surgical and gastr...
Management of culture-negative surgical site infections
Infections at the surgical site delays wound healing, prolongs hospitalization, increases morbidity and the overall costs. These issues are compounded when the postoperative infection is culturenegative. This article ou...