Sellar-parasellar epithelioid hemangioendothelioma
Journal Title: Journal of Neurological Sciences-Turkish - Year 2006, Vol 23, Issue 3
Abstract
Epithelioid haemangioendothelioma is a rare vascular tumor that presents histological features and biological behavior of low-grade malignancy. The authors report a case of malignant sellar-parasellar tumor. 36-year-old female, who had a history of head trauma 16 years before, presented with mild headache, and diplopia, 10 mouths later she presented Rapidly progressive ophthalmologic, ptosis and right amaurosis. CT-scan reveals an intra- or suprasellar mass with non-specific features, with calcifications and bone destruction. She underwent transcraneal partial resection of a suprasellar tumor. This lesion was histological diagnosed as epithelioid haemangioendothelioma that showed papillary endothelial hyperplasia. Immunohistochemically the neoplasm displayed striking positivity for CD31, CD34, EVGF, EVGF-RII and vimentin. The pathogenesis, correlation of histopathologic, radiology, and management of epithelioid hemagioepithelioma are reviewed. EVGF and it receptor can be useful of predictor behavior.
Authors and Affiliations
Citlaltepelt SALINAS-LARA, Daniel REMBAO-BOJÓRQUEZ, Martha TENA-SUCK, Hugo MALAGÓN
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