SEM based comparative study of diluted pharmaceutical agents silica and potassium chloride
Journal Title: International Journal of Pharmaceutical Chemistry and Analysis - Year 2017, Vol 4, Issue 3
Abstract
The morphological changes occurring because of trituration and solid dilution have been assessed by surface electron microscopy to follow medicinally active ingredients and validation of these findings became the objective of the study. Diluted Pharmaceutical agents Silica and Potassium Chloride were analyzed for comparison. The SEM presentation of the biochemic drugs support the idea that it is the unique characteristic change of the virgin drug substances produced because of trituration and solid dilution which is responsible for the changes in medicinal properties. The high intensity electron beam caused multiple fractures on softer molecules which helps distinguishing between lactose and the drug particles.
Authors and Affiliations
Anup Sharma, Bulbul Purkait
Keywords
Related Articles
- EP ID EP310583
- DOI 10.18231/2394-2797.2017.0015
- Views 154
- Downloads 0
Preparation of BSA-EA-MWCNTs submicron hybrid composite
Bovine serum albumin-egg albumin-multiwalled carbon nanotubes (BSA-EA-MWCNTs) submicron hybrid compositewas prepared by using suitable organic solvent and emulsifier as surface modifier. The prepared submicron hybrid com...
Synthesis and antimicrobial activities of some novel thieno [2,3-d]- Pyrimidin-4(3H)-One derivatives
Pain and inflammation are simultaneous responses in bacterial infections In current clinical practice the agents like antimicrobial drug are prescribed concurrently A POCl3 catalyzed efficient onestep and solventfree syn...
Brief update on Indian herbs and spices used for diabetes in rural area of Chhattisgarh
Ayurveda is a holistic science that was discovered several years ago. It is preventive as well as curative. Ayurveda is highly popular and mainly followed in India. India leads the world with largest number of diabetic s...
Complementary and alternative medicine: A new vista in dental management
Introduction: Since the dawn of civilization, mankind has been plagued by pathogen and its ensuing disease process and to overcome the outcome of the disease, various medical therapies have been formulated over the time....
Animal models of chronic kidney disease: Screening tool to investigate nephroprotective effects of natural products
Animals are used as experimental models to reproduce human diseases To date various animal models have been successfully developed by numerous methods to simulate human diseases including chronic kidney disease CKD Such...