SENNA OCCIDENTALIS SEED: IS IT HEALTH RISK OR POTENTIAL MEDICINE?
Journal Title: International Journal of Pharmacognosy - Year 2014, Vol 1, Issue 3
Abstract
In resource-limited localities of developing countries, potentially manageable, if not useful, resources may present actual health and agricultural cost due to poor management and lack of awareness of health risk consequences. Senna occidentalis L. (Fabaceae) is a pan-tropical weed with a wide range of medicinal uses, and in some parts used as famine food. Despite possible use as alternative food or medicinal ingredient of this plant, many reports blame its seed as the cause of hidden intoxication to humans and various domestic animals, leading to considerable economic consequences. As has been described by experimentally reproduced natural cases of many animal studies and few human cases, intoxication by seeds of this plant presented varied and non-specific disease manifestations. Induction of mitochondrial damage has been suggested as the mechanism of toxicity, yet the exactly responsible toxin has not been identified. Thus, it seems that Senna occidentalis seed is presenting potentially manageable health risks to animal and human health, especially in resource limited localities of developing countries. In this review, the possible health risks of Senna occidentalis seeds are discussed based on reports from naturally or experimentally intoxicated animal studies, human case reports, and related records. Some scientific claims on its potential medicinal uses are also presented.
Authors and Affiliations
Mebrahtom Gebrelibanos
Keywords
Related Articles
- EP ID EP427127
- DOI -
- Views 89
- Downloads 0
ANTIMICROBIAL SOCKS FORMULATION WITH SILVER NITRATE
Antiseptics and Disinfectants are extensively used in the health care industry and also equally in personal hygiene. Among the chemicals, silver has long been known to have antimicrobial activity. Development of new, eff...
ANTIOXIDANT ACTIVITY, PHENOLS AND FLAVONOID CONTENTS OF PLANT EXTRACTS
The extracts of two different plant were screened for their phenols, flavonoid and antioxidant activity by DPPH method for two locations. In this study seed oil and defatted seed cake extracts of M. azedarach and P. pinn...
IN-VITRO, EX-VIVO SKIN PERMEATION AND BIOLOGICAL EVALUATION OF 18-β-GLYCYRRHITIC ACID TRANSDERMAL PATCHES
Objective: a Transdermal patch is a promising approach that allows continuous input of drugs with short biological half-lives. 18 β-Glycyrrhizic acid (GA) is chemically pentacyclic triterpenoid which possesses powerful a...
SCAFFOLDS: A NOVEL TOOL FOR BONE TISSUE ENGINEERING
As life expectancy increases, malfunction or loss of tissue caused by injury or disease leads to reduced quality of life in many patients at significant socioeconomic cost. Bone disorders are of significant concern due t...
A REVIEW- PHYTOMEDICINES USED IN TREATMENT OF DIABETES
Diabetes mellitus (DM), both insulin-dependent DM (IDDM) and non-insulin dependent DM (NIDDM) is a common and serious metabolic disorder throughout the world. Traditional plant treatments have been used throughout the wo...