Sensory and motor blockade during spinal anaesthesia with 0.75% and 0.5% ropivacaine – A double-blind study
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2016, Vol 20, Issue 3
Abstract
Background: Spinal anaesthesiaproduces intense sensory and motor blockade as well as sympathetic blockade. Ropivacaine is a long-acting regional anaesthetic that is structurally related to Bupivacaine. It is developed for the purpose of reducing potential toxicity and improving relative sensory and motor block profiles. This study was undertaken to determine sensory and motor blockade profiles for 0.5% and 0.75% ropivacaine given intrathecally for perineal and lower limb surgeries. Material and Methods:A total of 100 patients were randomly divided into two equal groups. Group I received 0.5% and Group II received 0.75% isobaric Ropivacaine. After spinal anesthesia, sensory and motor blocks were assessed by pin prick test and Bromage scale respectively. Results: The results of our study indicate dose dependency. In both sensory and motor blockade cases, onset was quicker, intensity greater, regression slower, and duration longer with increasing concentrations. Conclusion: Intrathecal administration of 0.75% isobaric ropivacaine produced better quality of analgesia and motor block with negligible hemodynamic disturbances as compared to 0.5% ropivacainein perineal and lower limb surgeries.
Authors and Affiliations
Harish K, Sunil K S, Sudhaprasad .
A study of Assessment of Prevalence of Tubercular Infection and Tubercular Cervical Lymphadenitis in Rural school children of Nagamangala Taluka of Mandya District, Karnataka State
Background: Tuberculosis is one of the common communicable infections in our country. The present study reveals the status of Tubercular infection and Cervical Tuberculosis lymphadenitis in rural school children of Nagam...
Biochemical effects of two phytochemical mixture Eugenol with (+)-O-Methylarmepavine during the morphogenetic development of Blattella germanica
The German cockroach, Blattella germanica, is an important sanitary pest. It is cosmopolitan and abundant in homes and other human installations. Besides contaminating the places they live in with their excrements and ex...
Comparative study of serum uric acid and lactate dehydrogenase in preclampsia and normal pregnancy
Objectives: To compare serum levels of uric acid and lactate dehydrogenase in preeclampsia and normal pregnancy and to determine association of serum uric acid and lactate dehydrogenase with severity of preeclampsia. Stu...
Behavioral and Histological Observations after the Human Amniotic Epithelial Cells Transplantation in the 6-Hydroxydopamine Induced Parkinsonism Disease Model in Wistar Albino Rats
Several toxin-induced animals’ models simulate the motor deficits occurring in PD. Among them, the unilateral 6-hydroxydopamine (6-OHDA) model is frequently used in rats and has the advantage of presenting side-biased mo...
Glomerular Filtration Rate in Healthy Indian Adults by the Modification of Diet in Renal Disease Equation
Lamotrigine is an antiepileptic drug which by inhibiting voltage dependent sodium channels inhibits release of glutamate. Thus Dopaminergic system is removed from inhibitory influence of glutamate, causing increase in le...