Sentinel Lymph Node Biopsy in Lymphadenectomy for Prostate Cancer
Journal Title: Üroonkoloji Bülteni - Year 2016, Vol 15, Issue 2
Abstract
Performing the sentinel lymph node (SLN) biopsy during prostate cancer staging aims to provide more accurate nodal staging with low complications than pelvic lymph node dissection. SLN might be found outside the extended pelvic lymph node dissection template. Conventional SLN mapping is carried out after the injection of a 99mTcbased tracer and subsequent preoperative imaging; for example, lymphoscintigraphy and single photon emission computed tomography/ computed tomography. This approach allowed the detection of SLNs outside the extended lymph node dissection template in 3.6–36% of men with intermediate- and high-risk prostate cancer. Hereby, an overall false negative rate of sentinel SLNs was reported between 0% and 24.4% in the studies. To further refine the intraoperative sampling procedure, novel imaging methods such as fluorescence imaging have been introduced. Prospective randomized comparison studies are required to confirm the added benefit of sentinel template directed nodal dissection. There is a need to find a consensus about the topics such as Injection procedure, preoperative imaging, intraoperative sampling and dissection for performing SLN biopsy.
Authors and Affiliations
Cenk Acar, Henk van der Poel
Keywords
Related Articles
- EP ID EP228340
- DOI 10.4274/uob.625
- Views 101
- Downloads 0
Metastasis Targeted Therapies in Renal Cell Cancer
Metastatic renal cell cancer is a malignant disease and its treatment has been not been described clearly yet. These patients are generally symptomatic and resistant to current treatment modalities. Radiotherapy, chemoth...
Does the Future of Prostate Cancer Treatment Lie with Apoptotic Inducers?
Despite present-day clinical achievements which can extend the overall survival period, prostate cancer (PCa) related mortality remains a major problem. Resistance against apoptosis which consequently leads to disease pr...
Incidental Amyloidosis of the Seminal Vesicle: A Case Report and Review of the Literature
With a widely usage of prostate specific antigen (PSA) testing as a screening tool, number of prostate biopsy procedures and number of biopsy cores are increased because of the negative pathology results. As a result of...
Primary Adrenal Lymphoma: A Case Report
We report a case of primary adrenal lymphoma with a operation and a laparoscopic surgical resection. A 31-year-old male patient was complaining with back pain while he was examining a right adrenal tumor was detected on...
Urethral Leiomyoma: A Case Report
Leiomyomas are benign smooth muscle uterine masses most frequently seen in females during the period when they can give birth. Extrauterine leiomyomas are seen rare and where they are observed the most is the genitourina...