Sero-Prevalence and Coinfection of Hepatitis C Virus and Hepatitis D Virus in Patients with Hepatitis B Virus Infection in A Tertiary Care Hospital
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 7
Abstract
Background: Hepatitis virus infection is one of the most prevalent public health problems in developing countries. Hepatitis B (HBV) and Hepatitis C (HCV) viruses are main causative agents of chronic liver disease. This co-infection has been detected among patients with severe chronic hepatitis, cirrhosis, and inactive HBV infection. Hepatitis D virus (HDV) infection occurs either as a co-infection or super-infection in HBV carriers. Early screening of clinically diagnosed cases of viral hepatitis is essential for establishing diagnosis and treatment to prevent long term sequelae. About 380 million persons worldwide carry HBV and among them 5% have delta hepatitis. In association with HBV, HDV produces significantly more severe illness than HBV alone. Hepatic encephalopathy and fulminant hepatic failure were also common in HBV and HDV infected patients compared to those with HBV alone. Aims and Objectives: To find the rate of prevalence of HCV and HDV co-infections in patients with HBV infection in a tertiary care hospital. To do a comparative study of the rate of prevalence of hepatitis viral coinfections among male and female gender groups and also in patients with chronic and acute liver diseases. Materials and Methods: A total of 500 Venous blood samples were collected basing on the inclusion criteria and serum was separated and preserved at -20°C. The samples were tested for detecting HBV, HCV, and HDV markers by ELISA method, for HDV detection, HBV positive samples alone were considered. A total of 40 (8%) samples were HBsAg positive, followed by HCV 12 (2.4%), co-infection with HBV and HCV is 2 (0.4%) and 1(0.2%) with HCV and HIV co-infection. Conclusion: According to our study even though single infections are common, co-infections are seen more in age group of above 50yrs which may increase the risk of developing a chronic infection
Authors and Affiliations
Dr Vasanthi Rompicherla
Keywords
Related Articles
- EP ID EP213831
- DOI -
- Views 106
- Downloads 0
A Descriptive Study to Assess the Prevalence of Depression among the Adolscents People in Selected Community Area of Pune City
The objectives of the study were:- - To assess the prevalence of depression among adolescents people. -To associate the findings with selected demographic variables. A non-probability convenience sampling technique was...
Heterotopic Pregnancy in Natural Conception Cycle
Heterotopic pregnancy is defined as co-existence of intra uterine and extra uterine gestation. The incidence on theoretical basis is estimated to be 1 in 30,000 pregnancies. However more recent data indicates that the ra...
Noninvasive Markers for the Assessment of Liver Fibrosis and Cirrhosis in Egyptian Patients with Chronic Hepatitis C and Schistosomiasis Coinfection
To assess the role of noninvasive biomarkers in patients with chronic hepatitis C virus (HCV) and schistosomiasis coinfection and to correlate them with hepatic fibrosis and activity. This study was carried out on one hu...
Status of Hepatitis B, C, E and A in Healthy Asymptomatic Persons and Child Bearing Age Groups Females in Varanasi, U.P., India
Hepatitis B and C are common viral hepatitis, which can lead to cirrhosis or carcinoma of liver. These types of hepatitis are many times asymptomatic but can transmit the disease after blood transfusion and body fluid co...
Soft Tissue Lesions of Vulva: Histomorphology Vs Immunohistochemistry of These Rare Entities
Soft tissue lesions of the vulvo-vaginal tract are uncommon entities and are likely to be confused clinically with more common lesions like Bartholin’s cyst or fibro epithelial polyp. Due to a common cell of origin, both...