SERO-PREVALENCE OF DENGUE AND CHIKUNGUNYA, THEIR CO-INFECTION AND SEASONAL TRENDS OF THESE INFECTIONS AT A TERTIARY CARE HOSPITAL, AHMEDABAD, GUJARAT
Journal Title: International Journal of Microbiology Research - Year 2017, Vol 9, Issue 1
Abstract
Background: Dengue and chikungunya are an important mosquito-borne viral diseases of humans. There has been a recurrent phenomenon throughout the tropics in the past decade. Aedes aegypti mosquitoes are the common vectors for both dengue and chikungunya virus. In areas where both viruses co-circulate , they can be transmitted together. Aims & Objectives-This study was conducted to know the prevalence of dengue and chikungunya, their co-infection, Seasonal trends of these infections. Material and Methods- Study was performed at a tertiary care hospital Ahmedabad, Gujarat from July 2013 to July 2014 . Blood samples collected in plain tubes were tested for dengue Ig M antibody, NS1 antigen and Chikungunya Ig M antibodies. The month wise laboratory records were analyzed for seasonal variations. Results- In our study we tested total 8148 samples for dengue, chikungunya and its co-infection. Out of 8148 test requests, 4683 were requested for dengue and 1265 were requested for chikungunya alone while 1100 were requested for both dengue and chikungunya. A total of 992 samples were found positive for dengue out of 5783 total samples. Over all prevalence of dengue in our study was 17.15% (992/5783). In our study out of 4683 samples for dengue, overall prevalence of dengue was 20.26% (949/4683). Samples received for chikungunya were 2365 from which 795 were found positive. Over all prevalence of chikungunya was 33.61% (795/2365). Out of 1100 samples that were requested for both, 220 (20.0%) were positive for dengue, 231 (21.0%) were positive for chikungunya and 43 (3.9%) were positive for both. Seasonal trend showed a gradual increase in dengue and chikungunya positive started from August with a peak in September. Conclusion- Dengue and chikungunya viruses can cause dual infections in humans. Co-infections may result in illness with overlapping signs and symptoms, making diagnosis and treatment difficult. Hence, clinically suspected cases should be tested for both the pathogens in the endemic areas. With the urbanization that is occurring in India, the incidence of dengue infection is increasing theatrically. With assumption that cases of co-infection with dengue and chikungunya will become more prevalent in the future due to increased transmission of both viruses in various areas of India, enhanced and continuous surveillance for both dengue and chikungunya viruses is essential in the endemic areas for identification and characterization of these viral pathogens. This information will also help in the execution of proper measures to control the outbreaks caused by these emerging viral pathogens.
Authors and Affiliations
K. P. MODI
Keywords
Related Articles
- EP ID EP169948
- DOI -
- Views 116
- Downloads 0
PROBIOTICS AND PREBIOTICS
Probiotics and prebiotics are a special class of food products as their application in wellness of human beings is well established. Probiotics are living microorganisms that are taken as dietary supplements while prebio...
COMPARISON AND PCR CONFIRMATION OF ENTERIC PROTOZOAL ISOLATES IN AIDS PATIENTS- OPTIMIZING DIAGNOSTIC APPROACH IN DIFFERENT RESOURCE SETTINGS
Opportunistic infections in AIDS patients are a harbinger of death. In this study presence of enteric protozoa (Cryptosporidium parvum, Cyclospora cayetanensis, Enterocytozoon bienuesi) as causative agents of diarrhea in...
PLANT GROWTH PROMOTING CHARACTERISTICS OF RHIZOBIAL STRAINS ISOLATED FROM ROOT NODULES OF Vigna trilobata CULTIVARS
In the present study, six rhizobial strains were isolated from root nodules of Vigna trilobata plants raised in soils collected from geographically different areas in A.P., India. All the isolates were biochemically char...
OPTIMIZATION OF THERMOPHILIC PULLULANASE AND α-AMYLASE PRODUCTION BY AMYLOLYTIC YEAST
The amylolytic enzymes are the most important group of commercially produced enzymes such as α-amylase (EC 3.2.1.1) and debranching pullulanase (pullulan 6-glucanohydrolase; EC 3.2.1.41). In the present study, optimizat...
EVALUATION OF FUNGICIDES AGAINST POWDERY MILDEW (Erysiphe polygoni) OF FENUGREEK, Trigonella foenum graecum L.
In Rajasthan, fenugreek crop is attacked by a number of diseases. Powdery mildew of fenugreek is an important and serious disease caused by Erysiphe polygoni. A field experiment was conducted during Rabi 2012-13 and 2013...