Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran
Journal Title: International Journal of BioMedicine and Public Health (IJBMPH) - Year 2018, Vol 0, Issue 0
Abstract
Introduction: Toxoplasma gondii infects most warm-blooded vertebrates. Because of the immunodeficiency in hemodialysis patients, these individuals are at higher risk for reactivating chronic toxoplasmosis. Thus, the aim of this study was to investigate seroepidemiology of toxoplasmosis in hemodialysis patients of Ahvaz, southwest of Iran during 2015-2016. Methods: This is a cross-sectional study. A total of 160 participants, 80 hemodialysis patients (test group) and 80 healthy persons (control group) were randomly selected. IgG and IgM against T. gondii was measured by CLIA (Chemiluminescence) and ELISA (Enzyme-linked immunosorbent assay) tests. To analyze the data from Chi-square test, and SPSS statistical software of version 21 was used. Results: In hemodialysis patients, 35 (43.8%) and 25 (31.3%) were positive for the antibody of IgG by ELISA and CLIA, respectively. In healthy individuals, a positive result of 22 (27.5%) and 13 (16.3%) were obtained by ELISA and CLIA, respectively. In hemodialysis patients, 5 (6.3%) and 4 (5%) was positive by ELISA and by CLIA, respectively. In healthy individuals, a positive of 4 (5%) were obtained by ELISA and CLIA. The antibodies of IgG in hemodialysis patients was significantly higher than healthy individuals by ELISA and CLIA (P <.05). Conclusion: The prevalence of Toxoplasma in hemodialysis patients was higher than healthy subjects. Our finding showed a relatively high prevalence of the parasite among hemodialysis patients and healthy individuals in Ahvaz. So, the health authorities of Ahvaz city must pay more attention to control of the infection, especially in hemodialysis patients.
Authors and Affiliations
Forough Kazemi, Somayeh Fallahizadeh, Mohammad Hosein Feizhadad
Keywords
Related Articles
- EP ID EP262260
- DOI 10.22631/ijbmph.2018.55340
- Views 103
- Downloads 0
Spatial pattern of phenylketonuria disease determination using geographic information system in Lorestan province from 2006 to 2016
Introduction: Phenylketonuria(PKU) is a metabolic disorder that, if not detected and treated promptly, causes mental retardation. The use of the geographic information system (GIS) in favor of spreading the disease helps...
Prevalence and pattern of antibiotic resistance of gram-negative bacteria isolated from urinary tract infections in patients referring to Neka laboratories-Iran
Introduction: Urinary tract infection (UTI) is one of the most common bacterial infections. Increased drug resistance has identified the need to evaluate antibiotic resistance patterns to improve experimental therapy. Th...
Comparison of the effectiveness of different oral glucose lowering drugs in fasting patients with type II diabetes
Introduction: Type 2 diabetes is the most common metabolic diseases in developed and developing countries with no effective treatment options. This study purpose was to compare different regimens of oral anti-diabetic th...
The effect of education based on the Health Belief Model in mothers about behaviors that prevent febrile seizure in children
Introduction: Fever is one of the most concerning issues in public health, which occurs fairly frequently and is a precursor for the occurrence of seizure in childhood between ages of 6 months to 6 year children. Therefo...
A comparative study on the effect of the California Book and relative value of services on the costs of hospitalization for common surgeries in selected hospitals of Sanandaj, Iran
Introduction:Tariff determination is one of the important tools for policy making which governments use to intervene in the health market. The aim of this study was to compare California Book effect and relative value of...