Seronegative Myasthenia Gravis Presenting as Dysphagia in a Young Male- A Diagnostic Dilemma
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2022, Vol 2, Issue 11
Abstract
21year old gentleman presented with insidious onset, gradually progressive dysphagia for 2 weeks. There was no other associated signs or symptoms. Initial blood workup, radiological investigations and diagnostic interventions were non-contributory.In the meantime, dysphagia worsened and was found to be progressive with advancement ofthe day. Oesophageal manometric studiesshowedgradual weakeningof peristaltic contractions after a string of repetitive swallows. Repetitive nerve stimulation test and edrophonium test weresuggestive of Myasthenia Gravis; Anti-acetylcholine receptor antibody and anti-MuSKantibody were negative. He was initiated on Pyridostigmine and had improvementof dysphagia after a few days. Hehas now achieved remission. Hence, we present a curious case of Seronegative Myasthenia Gravis presented withonly dysphagia and had complete recovery after proper diagnosis and treatment.
Authors and Affiliations
Dr. Sudipto Chakraborty, Dr. Sreemanti Bag
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