Seropositivity of hepatitis b surface antigen in tertiary care centre: issues & considerations
Journal Title: International Journal of Medical Research and Review - Year 2016, Vol 4, Issue 10
Abstract
Background: Hepatitis B virus (HBV) infects more than 300 million people worldwide and is common cause of liver disease and liver cancer. HBV, a member of the Hepadnaviridae family, is a small DNA virus with unusual features similar to retroviruses. HBV replicates through an RNA intermediate and can integrate into the host genome. The unique features of the HBV replication cycle confer a distinct ability of the virus to persist in infected cells. Aims & Objective: This study was designed to determine HBsAg Seropositivity among rural population attending inpatients and outpatients at tertiary care center with special consideration to childbearing age women. Material & Method: This retrospective study was conducted in the Department of Microbiology for three months in a tertiary care center catering rural population. A total of 1463 patients attending outdoor and indoor, were screened for HBsAg by lateral flow based rapid immunochromatographic card test (ICT) manufactured by J Mitra & Co Pvt Ltd. Results: Seropositivity of HBsAg was 41/1463(2.80%). Seropositivity was seen more in males 27/756(3.57%) as compared to females 14/707(1.98%). Age range 31-45 years was found to have highest prevalence rate with seropositivity of 15/279(5.38%). Among patients screened for HbsAg, we observed seropositivity of 2.37% (12/505) among women of childbearing age with age range 16 to 45 years. Conclusion: Findings in this study significantly contribute to the understanding of actual epidemiology of HBsAg in rural population especially women of childbearing age. Therefore, we should make efforts to prevent HBV infection by focusing on associated risk factors.
Authors and Affiliations
Surinder Kumar, Pallavi Sayal, Diksha Budhani, Sumit Kumar
Keywords
Related Articles
- EP ID EP231141
- DOI 10.17511
- Views 114
- Downloads 0
Association between mean platelet volume and Microalbuminuria in Type 2 Diabetes Mellitus Patients
Background: Type 2 DM is characterized by increased platelets activation, hence platelet functional markers like the mean platelet volume (MPV) can play a vital role in identifying subjects at high risk of developing mic...
Effects of Escitalopram on C reactive protein in patients of depression
Objective: To study the anti-inflammatory activity of Escitalopram in newly diagnosed patients of depression. Materials and Methods: 100 Newly diagnosed patients of Depression as per ICD 10 (International classification...
Morphologic study of nutrient foramina in dried tibia and its clinical implications
Introduction: Diaphyseal fractures of tibia cases are common in orthopaedics and traumatology department. While planning a bone graft for a patient with trauma or tumour resection, the vascularity of the left over bone i...
Spectrum of abnormal epithelial lesions of cervix in a tertiary care teaching hospital in South India
Introduction: Cervical cancer is the leading cause of death in developing countries like India. Cervical cytology by papanicolaou (pap) smears is an effective means of screening for cervical premalignant and malignant le...
Study of relationship between ABO & Rh blood group and type 2 diabetic mellitus
Background & Objective: The findings of Arid et al, in 1953 regarding association between carcinoma of stomach and B blood group and successively in 1954 regarding association between peptic ulcer and O blood group opene...