SEROPOSITIVITY OF IgM DENGUE (ELISA) AMONG SUSPECTED CASES OF DENGUE- A STUDY FROM TERTIARY CARE CENTRE IN PUNJAB
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 21
Abstract
BACKGROUND Dengue fever is the most common cause of arboviral disease worldwide. In India and other tropical countries, it remains an important differential diagnosis for a febrile illness. The disease burden is growing very fast in various countries including India. Aims and Objectives- This study was done to find the seropositivity of Dengue (IgM Dengue by ELISA) in blood samples taken from suspected cases of dengue fever. MATERIALS AND METHODS This is a hospital-based descriptive study, conducted at the serology laboratory in the Department of Microbiology at a tertiary care centre from January 2017 to December 2017. Blood samples were received in the department from indoor and outpatients who were suspected to have dengue fever. A total of 1347 samples were collected in 12 months and these samples were processed for IgM Anti-Dengue antibodies (ELISA). RESULTS The male-to-female ratio of suspected cases was 1.23:1. Adults constituted 855 samples, while the remaining 492 were of paediatric population. IgM Dengue ELISA was found positive in 457 samples (Positivity rate 33.92%). Dengue positive samples were constituted by 316 adults and 141 paediatric patients giving a positivity rate of 36.95% and 28.65% respectively. The seropositivity among male and female was 35.12% and 32.45% respectively. Maximum number of dengue positive samples were detected during the month of October. CONCLUSION Prompt diagnosis is the key to better management and decreased morbidity/ mortality. In our study, a commercial kit (Panbio IgM Dengue ELISA) was used for diagnosis of dengue fever, which showed a seropositivity of 33.92%. Various steps at multiple levels (Curb mosquito breeding, early diagnosis and treatment) are needed to stop the growing number.
Authors and Affiliations
Shavi Nagpal, Aroma Oberoi
Keywords
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- EP ID EP431615
- DOI 10.14260/jemds/2018/575
- Views 77
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