Serum C Reactive Protein levels in Stable COPD Patients Attending a Tertiary Care Centre – A Prospective Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 8
Abstract
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality throughout the world. C-Reactive protein (CRP) is found in blood plasma, which rises in response to inflammation. A prospective study was conducted in a tertiary care teaching hospital to assess the levels of CRP in stable COPD patients. 100 patients with stable COPD without co-morbidities attending the respiratory OPD were recruited. CRP levels were estimated and patients were followed up for a period of 6 months to check CRP levels serially every 2 months. During exacerbation, CRP was estimated and repeated after 2 weeks of remission, if still positive, again repeated after 2 weeks. Average CRP level was high in a significant number of COPD patients. As the stage of COPD advanced CRP levels were also significantly raised. By applying ANOVA test, average CRP between different stages of COPD was found to be significantly high. Even though current smokers and reformed smokers had high average CRP, statistical significance in mean CRP between them and non smokers were not found. There was a negative correlation between CRP & BMI, but was not statistically significant. There was no significant relationship of CRP with age of the patients. There was negative correlation seen with oxygen saturation, with a significant p value. It was concluded that systemic inflammation is inherent to COPD, independent of smoking status, age & BMI but correlates with disease severity
Authors and Affiliations
Dr Sophia Philip
Keywords
Related Articles
- EP ID EP489660
- DOI -
- Views 52
- Downloads 0
Overview of Referred Obstetric Patients and Their Outcome in Tertiary Care Hospital
Background: The key factors contributing the adverse maternal outcomes are lack of trained birth attendants, lack of education, low status of women in society, poor families, financial dependency of women, and delay in s...
Encephalotrigeminal Hemangiomatosis: Two Case Reports
Encephalotrigeminal Hemangiomatosis also known as sturge- weber syndrome is specifically congenital, non-hereditary, rare condition occurring with a frequency of 1:50,000 live births, with equal predilection for either s...
Retrospective analysis of blood donor deferral pattern at a tertiary Care Centre
Blood transfusion plays an essential role in patient management and can be a vital, life-saving procedure. The provision of blood for transfusion largely depends on the availability of healthy voluntary blood donors but...
Assess the Knowledge Regarding Self-Care Management among Newly Diagnosed Type 2 Diabetic Clients Attended Out Patient Department at Parshuram Hospital, Ghanekhunt-Lote, Ratnagiri Dist. Maharashtra State
Background of the study: Diabetes mellitus is a major public health concern worldwide. There will be an alarming increase in the population with type 2 diabetes in developed and developing countries over the next two dec...
Quality of Life in Rheumatoid Arthritis patients taking combination DMARDs
Objective: To assess the QOL of RA patients taking non biological combination DMARDs Material & Methods Study Design: Open Label Study Treatment naïve or chronic cases of RA in age group of 18-60 years of both sex with R...