Serum Creatinine and Uric Acid Levels in Hypothyroid Patients: A Cross Sectional Study
Journal Title: Journal of Enam Meical College - Year 2013, Vol 3, Issue 2
Abstract
Background: Hypothyroidism is associated with many biochemical abnormalities including increased serum creatinine and uric acid levels. Many studies were done abroad regarding serum creatinine and uric acid levels in hypothyroid patients. We designed this study in our population for evaluation of serum creatinine and uric acid levels in hypothyroid patients. Objective: To assess serum creatinine and uric acid levels in hypothyroid patients and to find out relationship of creatinine and uric acid levels with severity of hypothyroidism. Materials and Methods: This retrospective cross sectional study to evaluate the serum creatinine and uric acid levels of hypothyroid patients and to find out relationship of hyperuricemia and hypercreatininemia with severity of hypothyroidism was done in the department of Biochemistry, Bangabandhu Sheikh Mujib Medical University, Dhaka. Results were compared with that of age and sex matched healthy euthyroid controls. Statistical analyses were performed by using SPSS for Windows version 10.0. ANOVA and unpaired ‘t’ tests were done to see the significance among the groups and between groups respectively. Pearson’s correlation coefficient test was done to see the correlation of serum creatinine and uric acid levels with the severity of hypothyroidism. Results: Mean serum creatinine and uric acid levels in cases were 1.38 ± 0.53 and 7.00 ± 2.54 mg/dL respectively compared to 1.01 ± 0.17 and 5.21 ± 1.35 mg/dL in controls. Conclusion: Mean serum creatinine and uric acid levels were found significantly higher in hypothyroid patients compared to controls. These findings suggest that hyperuricemia and hypercreatininemia are associated with hypothyroidism. Therefore, patients presenting with these biochemical abnormalities are recommended to be investigated to explore hypothyroidism.
Authors and Affiliations
Md. Aminul Haque Khan, Md. Ishaque Majumder, Md. Mozammel Hoque, Md. Fariduddin, Forhadul Hoque Mollah, Iqbal Arslan
Keywords
Related Articles
- EP ID EP36172
- DOI https://doi.org/10.3329/jemc.v3i2.16129
- Views 370
- Downloads 0
Outcomes following Purely Endoscopic Endonasal Resection of Pituitary adenomas
Background: The use of endoscope for the management of pituitary adenoma is not new. The better magnification and illumination provided by the endoscope gives better outcome than microscopic pituitary surgery. Objectiv...
Mid Aortic Syndrome (MAS)
Not available
Role of Visual Inspection of Cervix with Acetic Acid (VIA) in Detecting Precancerous Lesions of Cervix
Background: Carcinoma of cervix is the most common malignancy in female and a major public health problem worldwide. It is the leading cause of death from cancer among women in low resource settings. In Bangladesh, mor...
HIV Epidemic Situation in Bangladesh: An Overview
Bangladesh is one of the countries of the world where there is low human immunodefciency virus (HIV) prevalence, but is still considered to be at high risk because of presence of many risk factors for spread of HIV....
Scenario of Fine Needle Aspiration Cytology of Neck Masses in a Tertiary Care Hospital
Background: Masses in the neck are very common and these may range from inflammatory to neoplastic lesions. Fine needle aspiration cytology (FNAC) is a simple, quick and minimally invasive procedure that is well recogniz...