Serum levels of vitamin D in women treated at rheumatology services in Lima
Journal Title: International Journal of Clinical Rheumatology - Year 2019, Vol 14, Issue 3
Abstract
The objective of this study was to determine the vitamin D status in women ≥50 years of age who were treated at rheumatology services in Lima, Peru, and determine the proportion of patients who require correction of vitamin D deficiency. A total of 157 women were evaluated; 25-hydroxyvitamin D [25(OH) D], intact Parathyroid Hormone (PTH), calcium and serum phosphorus were measured. The mean age was 63.3 ± 8.6 years, and most were diagnosed with fibromyalgia (50%) and osteoarthritis (30.57%). The mean [25(OH) D] value was 18.7 ± 6.7 ng/mL, and no differences in calcium, phosphorus, [25(OH) D] and PTH values were found between the subgroups stratified by age. No correlation was found between age and [25(OH) D] (r =0.099; p=0.212). We found a weak direct correlation between age and PTH (r=0.183; p<0.05) and a weak inverse correlation between [25(OH) D] and PTH values (r= -0.179; p<0.05). We found [25(OH) D] values<20, between 20-30 and ≥30 ng/mL in 58.6%, 36.9% and 4.5% of patients, respectively. The average [25(OH) D] values were lower in obese patients than in non-obese patients (16.94 vs. 19.42 ng/mL; p<0.05). Vitamin D deficiency was prominent in rheumatic patients, and in approximately 60%, we found vitamin D values <20 ng/mL, which require correction. Identifying and treating vitamin D deficiency is recommended because of the impact on different health parameters in these patients.
Authors and Affiliations
Luis Fernando Vidal Neira, Rasec Morales Olazabal, Kori Cueva Tovar, Nathaly Pasapera Albán, Maritza Vidal Wilman, José Luis Rojas Vilca
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