Serum β HCG as a predictor and potent marker for pregnancy induced hypertension
Journal Title: International Archives of Integrated Medicine - Year 2019, Vol 6, Issue 3
Abstract
Background: Hypertensive disorders are also responsible for perinatal mortality and morbidity. Pre-eclampsia is a risk factor for stillbirth, IUGR, LBW, Preterm delivery, Respiratory distress syndrome, and admission in the neonatal intensive care unit. Hypertensive disorders account for 8-10% of all preterm births. Aim of the study: This study was conducted to predict gestational hypertension by using serum beta HCG and thereby to follow up the risk patients and to reduce both maternal and perinatal morbidity and mortality. Materials and methods: A prospective study was done to determine the role of βHCG in 100 pregnant women in their second trimester (13-20) weeks, attending Tirunelveli medical college OPD. Duration of study was from March 2018- January 2019. Routine antenatal investigations were done. 5 ml of venous blood sample was collected and tests were carried out. Estimation of serum beta HCG level was done by enzyme-linked fluorescence immunoassay. In the antenatal clinic, the patients were followed up. Results: From the study, it was found, women who have elevated βHCG values in 13-20 weeks were at increased risk of developing PIH. For any test to be used as screening test it should have good sensitivity, specificity, and positive predictive value. In this study, β HCG had Sensitivity – 71.4%, Specificity - 87.1%. Conclusion: While comparing patients with normal BP and pre-eclampsia - βHCG values are elevated in patients with preeclampsia. The sensitivity and specificity of βHCG are very low to be useful as a mass screening marker on its own and therefore it should be combined with other serum markers and ultrasound parameters like Doppler study of uterine vessels, which will help in improving its role as a screening tool.
Authors and Affiliations
Sheba Rosatee Victor, D Jayalakshmi
Keywords
Related Articles
- EP ID EP674830
- DOI -
- Views 156
- Downloads 0
Comparison of caudal tramadol versus caudal fentanyl with bupivacaine for prolongation of postoperative analgesia in pediatric patients
Introduction: Caudal block is one of the most popular and commonly used regional anaesthetic procedures in paediatric patients for most surgeries below the umbilicus. Because of the short duration of analgesia with bupiv...
Radiological evaluation of Ovarian Dermoid
Background: Ovarian dermoid cyst is the most common ovarian neoplasm. It accounts for ~15% of all ovarian neoplasms. They tend to be identified in young women, typically around the age of 30 years. These slow-growing tum...
Cytodiagnosis of Gout - A rare case report
Fine Needle Aspiration Cytology (FNAC) is very valuable in diagnosis of a periarticular lesions and thereby confirming the nature of an associated arthritic process. Gout is a disorder of uric acid metabolism that causes...
Histopathological features and immunoflorescence patterns in skin lesions
The diagnosis of vesiculo-bullous lesions and many other diseases is fundamentally based on the microscopic study of cells and tissues. This diagnostic method remains the standard, by which all other diagnostic tests are...
A clinical study of emphysematous pyelonephritis
Background: Emphysematous pyelonephritis should be suspected in every diabetic patient, presenting with features of acute pyelonephritis. E.coli is the most common organism associated with EPN. Aim: To study the clinica...