Serum vitamin D concentrations among 609 patients of Endocrine Outpatient Clinic – preliminary report
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 11
Abstract
Introduction. Only scarce data have been published regarding serum vitamin D status in adult population in Poland. The preliminary results of the retrospective assessment of vitamin D status in adult patients of our outpatient Clinic, based on records from the databases of Central Laboratory, Bielański Hospital are presented.Material and methods. From the database of the Central Laboratory of Bielański Hospital, Warsaw, we selected 908 records of serum 25OHD measurements made in years 2007-2009 for the 609 normocalcemic patients: men and women, in wide range of age.Results. The mean vitamin D concentration was 19.86 ± 16.08 ng/ml in the whole examined population. Vitamin D levels above 30 ng/ml were found only in 52 patient (8.54% of subjects). Vitamin D insufficiency (20-30 ng/ml) was found in 23.8%, moderate vitamin D deficiency (10-20 ng/ml) was found in 44.9%, and overt hypovitaminosis D (> 10 ng/ml) in 21.8% of subjects. Vitamin D concentrations was highest in the younger patients, significantly higher in group < 50 years vs. > 70 years of age (adequately 18.43 ± 10.31 ng/ml vs. 15.93 ± 9.00 ng/ml, p = 0.02). A linear regression analysis shown a slight significant association between age and serum vitamin D concentrations. Serum 25OHD concentrations in fractured patients was found to be significantly lower than in non-fractured subjects. In patients taking several OTS preparations of vitamin D, the serum levels of 25OHD after 6-18 months of such as treatment did not differ significantly from basal results and still were low.Conclusions. The prevalence of low vitamin D concentration in Poland is very high and is associated with aging. Uncontrolled vitamin D supplementation from OTS sources (dietary supplements, multivitamins) is not effective.
Authors and Affiliations
Waldemar Misiorowski, Tomasz Słyk, Aleksandra Wycisk, Wojciech Zgliczyński
Keywords
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