Significance of Androgen/Estrogen ratio in Prostate Cancer and Benign Prostatic Hyperplasia: An Eclipsed Truth
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2017, Vol 3, Issue 6
Abstract
The International Agency for Cancer Research (IARC) has shown a low incidence of prostate cancer in East Asian countries as compared to western counterparts although its incidence in India is rising as well. As endogenous testosterone production physiologically declines with increasing age while life expectancy continues to rise; recognition of testosterone deficiency syndrome (TDS) is currently increasing. The hormonal regulation of prostate cancer is not limited to a role for androgens and we propose that androgens in combination with estrogens are required for PCa. So this is the primary approach to find the significance of Androgen and Estrogen ratio in Prostate cancer and benign prostatic hyperplasia that is being eclipsed for years by an androgen dominated interest.
Authors and Affiliations
Reshu Tewari 1 , Anurag Bajpai 2 , Jaswant K. 1 , Bijay KM 3 , S. M. Natu 4 , Apul G. 5 , D. Dalela 6 , K. S. Sodhi 7 , Jasbir S 8
Keywords
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- EP ID EP569134
- DOI 10.22192/ijcrms.2017.03.06.008
- Views 131
- Downloads 0
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