Significance of Relationship between Platelet Indices and Hyperlipidemia in Predicting Ischaemic Events
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 5
Abstract
Abstract: Atherosclerosis begins with damage to the endothelium. It’s caused by high blood pressure, smoking, or high cholesterol. That damage leads to the formation of plaque.When bad cholesterol, or LDL, crosses the damaged endothelium, the cholesterol enters the wall of the artery. That causes your white blood cells to stream in to digest the LDL. Over years, cholesterol and cells become plaque in the wall of the artery.This was a prospective case control study conducted between June to August 2016 in the Department of Pathology in collaboration with Department of Cardiology, General medicine and Department of Biochemistry of Prathima Institute of Medical Sciences, Karimnagar.The study and control groups were found to be age and sex matched statistically. Hence, no bias in the results was observed due to age and sex in the results. Out of the total 80 cases of hyperlipidemia, 47 were males and 33 were females. The patients fell into the age group between 23 to 83 years. Mean age in study group - 53.65 years and in control group - 56.35.All three PVI were significantly higher in hyperlipidemic cases than the normolipidemic controls (p-value <0.05). Isolated hyperlipidemia showed no significant difference in platelet parameters than controls (p-value >0.05). Hyperlipidemia associated with other diseases like diabetes, hypertension and CAD showed significantly lower platelet counts and significantly higher platelet indices (p-value <0.05) than controls. Keywords:Hyperlipidemia, Platelet indices, ischemia
Authors and Affiliations
Syeda khadija Fatima, Srikanth Shastry, G. Anandam
Keywords
Related Articles
- EP ID EP372646
- DOI -
- Views 67
- Downloads 0
Study to Find Out the Risk Factors and Prevalence of Very Low Birth Weight and Extremely Low Birth Weight Babies in Terms of Mortality in Early Neonatal Period in Babies Admitted to a Tertiary Care Teaching Hospital in Eastern India
Abstract: Preterm birth is one of the major clinical problems in neonatology as it is commonly associated with perinatal mortality, serious neonatal morbidity. To find out the risk factors and morbidities of very low bir...
Comparative Study of Clinical Performance of the I-Gel with LMA Proseal: A Randomised Control Study
Abstract: The major responsibility of anaesthesiologist is to provide adequate ventilation to the patient. The most vital element in providing functional respiration is airway. Supraglottic airway devices have become a s...
Evaluation of Total Antioxidant Activity and Its Relation with Serum Uric Acid in North Indian Elderly
Aging process has been found to be associated with biomolecular destruction which in turn responsible for progression of age related complications. It is conceivable that alteration in plasma antioxidant reserve along wi...
Efficacy of Miniature Punch Grafting Followed By Puvasol Therapy in Refractory Stable Vitiligo
Abstract: Vitiligo affects approximately 2% of the worldwide population regardless of race, ethnic background or gender. When the medical methods are not successful, surgical procedures may be considered with the aim of...
Candida Albicans Endocarditis in a Haemophiliac Patient with Chronic Kidney Disease: A Case Report
Haemophilia is an X-linked recessive clotting disorder. Chronic kidney disease is a rare complication in haemophilia. The need for a long term hemodialysis in such patients necessitates the use of indwelling central veno...