Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease): A Case Report with Review of Literature

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Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease): A Case Report with Review of Literature

Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 3

Abstract

Sinus Histiocytosis with Massive lymphadenopathy, also commonly known as Rosai-Dorfman Disease is a rare non neoplastic histiocytic disorder first described by Rosai and Dorfman, seen predominantly in childhood and young adults. It is characterized by fever, painless massive cervical lymphadenopathy and elevated ESR levels. RDD is often misdiagnosed as lymphoma, tuberculosis or metastatic malignancy, so it is important to distinguish it from these conditions as the modes of treatment are different. Here we report a case of 18 years old male presenting with massive lymphadenopathy. Morphological findings demonstrated Emperipolesis consistent with a diagnosis of Rosai-Dorfman disease. Clinical and cytological aspects of the disease are discussed as a rare cause of lymphadenopathy.

Authors and Affiliations

Dr Rajat Gupta

Keywords

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EP ID EP213427
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