SMOKING HABIT AND BRONCHIAL HYPERRESPONSIVENESS AMONG POTROOM WORKERS IN ALUMINIUM INDUSTRY
Journal Title: Acta Medica Medianae - Year 2005, Vol 44, Issue 1
Abstract
Changes of pulmonary function in some potroom workers occur several hours on beginning of their work (early reaction), or after work (late reaction) either because concentrations of damaging agents are high or reactions of workers’ organism are inhanced. Numerous studies, especially the tests of bronchial responsiveness confirmed bronchial hyperreactivity as the reason of attacks. Results of numerous studies indicated the connection between exposure at workplace, smoking habit, non-specific air pollutants on one hand and the appearance of bronchial asthma on the other. The aim of the study was to determine the relationship between smoking habit and intensity of bronchial hyperreactivity in potroom workers in aluminium industry. We examined 133 potroom workers (mean age - 39,73; mean duration of exposure - 17,17 years) and 35 unemployed persons belonging to the control group not having been exposed to the agents occuring in the occupational environment. Smoking habit was highly frequent in potroom workers (62,4%) and the situation was similar with the control group (62,8%). Bronchial hyperresponsiveness was registered in 36,8% of the exposed workers and in 34,4% of the workers in the control group (an insignificant difference). Analysing spirometric values in potroom workers regarding their smoking habit, we found a significant difference only for small airways’ values (MEF25, MEF50, MEF25/75,). Hyperreactors with smoking habit had more pronounced bronchoobstruction (FVC-29,2%; FEV1 - 34,2% when compared to hyperreactors non-smokers (FVC - 18,1%, FEV1 - 20,5%). Hyperreactors ex-smokers had more pronounced reactions to meatcholine test (FCV - 29,2%, FEV1 - 31,7%) when compared to non-smokers. We concluded that smoking habit could intensify bronchial hyperresponsiveness even in ex-smokers.
Authors and Affiliations
Ljiljana Kezunovic, Jovica Jovanovic, Ankica Ivanovic, Mensud Grbovic
ABNORMALITIES OF EXTERNAL GENITALIA AND GROIN HERNIAS IN THE CITY OF KARAK IN THE SOUTH OF JORDAN
The aim of this prospective study was to find out the incidence of groin hernias and external genitalia abnormalities in children in the City of Karak at the south of Jordan for referral and early treatment, as well as t...
JUVENILE GIANT FIBROADENOMA MAMMAE - CASE REPORT
Fibroadenoma mammae is a mixed fibroepitelioma benign breast tumor caused by proliferation of epithelium and fibrovascular stroma. It makes 7% of all nodular breast changes. Most often, it occurs in women aged 30 to 40 y...
ANTIOXIDANT AND PRO-OXIDANT EFFECT OF ASCORBIC ACID
Free radicals attack proteins, lipids, enzymes andDNAcausing pathological changes in organism. There are many mechanisms that organism uses to fight against free radicals. Ascorbic acid is one of the strongest reducers...
EFEKTI VERAPAMILA NA SERUMSKU KONCENTRACIJU NATRIJUMA I KALIJUMA I PATOHISTOLOŠKE PROMENE PRIKAZANE HE METODOM U EKSPERIMENTALNOJ GENTAMICINSKOJ NEFROTOKSIČNOSTI
Analizirano je delovanje verapamila na segmente nefrona bubrega pacova u gentamicinskoj nefrotoksičnosti. U životinja tretiranih gentamicinom (100 mg/kg tt/24 h) zabeležene su značajne promene u korteksu, posebno na prok...
PTERIDINES - METABOLIC FUNCTIONS AND CLINICAL DISORDERS
Pteridines are widely distributed compounds in nature, associated with numerous important physiological functions. BH4 is classified as unconjugated pteridine distinct from folic acid and its metabolites folates represen...