Some aspects of pharmacotherapy of low back pain connected with degererative spine disease

Journal Title: Reumatologia - Year 2006, Vol 44, Issue 6

Abstract

Pain disability in the course of degenerative spine disease produces the pathological deterioration of quality of life and ability to work. Pain is usually associated with changes of the spinal motion segment and part of the neuro-vascular system located in the vertebral canals. The types of pain are different because of different mechanisms of its origin. It should be included in the therapeutic procedure if the standard analgesic treatment is insufficient. The authors distinguish 3 essential clinically selected types of pain: • musculoskeletal (nonspecific, mechanical, pseudoradicular) referable to the intervertebral disc, facet joints: traumatic and inflammatory origin, • radicular neuralgia caused by compression and inflammation, including also neuropathic pain. • neurogenic intermittent claudication type of pain related to acquired spinal canal stenosis: generated by compression and radicular ischaemia. We describe therapeutic approaches in different spine pains according to the pathomechanism of their origin.

Authors and Affiliations

Tadeusz Styczyński, Robert Gasik, Bohdan Pyskło

Keywords

Related Articles

Low oxygen tension promotes redifferentiation of dedifferentiated human articular chondrocytes in vitro

Articular cartilage degradation is a main cause of joint destruction in rheumatic diseases. An attractive possibility for cartilage repair is the use of cultured in vitro chondrocytes. However, cultured chondrocytes unde...

Leflunomid w terapii chorych na reumatoidalne zapalenie stawów – wstępna obserwacja efektu terapeutycznego i objawów niepożądanych

Skuteczność i bezpieczeństwo leczenia leflunomidem chorych na reumatoidalne zapalenie stawów poddano wstępnej ocenie. Lek w tabletkach podawano 158 chorym (150 kobiet i 8 mężczyzn) przez 3 dni po 100 mg/dobę, następnie p...

Autoantibodies to the platelet-derived growth factor receptor in systemic sclerosis

This article briefly reviews the structure and function of platelet-derived growth factor and its receptor. The authors describe presence of autoantibodies against platelet-derived growth factor receptor in systemic scle...

Zespół Reitera – wieloletnie obserwacje

W pracy przedstawiono wieloletnie obserwacje pacjentów z rozpoznaniem zespołu Reitera. Analizowano historie choroby 100 chorych z rozpoznaniem zespołu Reitera, hospitalizowanych w Śląskim Szpitalu Reumatologiczno-Rehabil...

SAPHO-a case report

The case of the 36-year old female patient with osteosclerotic and osteolotic osteoarticular changes and hyperostosis of the spine is presented. She had suffered from spinal pain for ten years and she had clavicular pain...

Download PDF file
  • EP ID EP128867
  • DOI -
  • Views 67
  • Downloads 0

How To Cite

Tadeusz Styczyński, Robert Gasik, Bohdan Pyskło (2006). Some aspects of pharmacotherapy of low back pain connected with degererative spine disease. Reumatologia, 44(6), 335-338. https://europub.co.uk./articles/-A-128867