Some Serum Biochemical Changes in Yankassa Sheep Experimentally Infected with Single and Mixed Trypanosoma Congolense and Haemonchus Contortus
Journal Title: Journal of Veterinary Advances - Year 2012, Vol 2, Issue 3
Abstract
Serum biochemical profile was determined in Yankassa Sheep experimentally infected with single and mixed infection of Trypanosoma congolense and Haemonchus contortus over a period of sixty days. An upward trend was observed in serum globulin concentration for trypanosoma congolense and heamonchus contortus (TcHc) and haemonchus contortus and Trypanosoma congolense( HcTc) infected animals at Day 14 post-infection (PI). Thereafter a significant decrease (P>0.05) was observed. Hypoalbuminaemia occurs in TcHc infected animals (P> 0.05) and it may be attributed to high level of parasitaemia in the group. There was fluctuation in the level of total protein, the increase or decrease may have been caused by the severity of the infection. There was an increase in the serum bicarbonate level in TcHc and HcTc infected animals, (P> 0.05), this may be due to generation of bicarbonate ions by the kidney which may increase in trypanosome infection. While the drop can be due to acidosis associated with anaemia, renal malfunction and release of toxic metabolites such as free-fatty acids by trypanosomes. The observed decrease in Serum Potassium (K+) level in trypanosome-infected groups may be as a result of red blood cell (RBC) destruction, which is a source of extra serum K+ and that a rise in K+ level coincides with a fall in RBC level. There was a decreased in Serum Sodium(Na+) level, which agrees with the known physiological observation that increases in plasma K+ levels, is always accompanied by subsequent fall in plasma levels of Na+. The mechanism of Na+ removal from the plasma is believed to be partly intracellular among other serum components. This theory is supported by significant increase in Serum Potassium (K+) in the plasma, since any movement of Na+ intracellularly is accompanied by the displacement of K+ from the intracellular compartment into the plasma, while K+ movement out of the cell may lead to the retention of Na+ intracellularly. A coresponding fall in Serum Chloride (Cl-) level was also observed in TcHc and HcTc groups (P> 0.05). It is generally believed that a fall in Cl- level always follows a fall in Na+ level which was observed in the same infected groups.
Authors and Affiliations
Okaiyeto S. O , Ajanusi O. J , Sackey A. K. B. , Tekdek L. , Danbirni and Ernest A
Keywords
Related Articles
- EP ID EP145761
- DOI -
- Views 95
- Downloads 0
Organ Weights, Carcass Characteristics and Blood Chemistry of Broiler Birds Fed Graded Levels of Mucuna Utilis Leave Meal
The effect of feeding graded levels (0, 5, 10 and 15%) of mucuna utilis leaf meals (Velvet bean) to broiler chicks on organ weights, carcass characteristics and blood chemistry was investigated. One hundred and eighty (1...
Assessment of Heavy Metal Residues in Hides of Goats Singed with Tyres, and the Effect of Boiling on the Heavy Metal Concentrations in the Hides
Tyres are reported to contain toxic materials which could pose health threats to humans. However, some butchers in Ghana singe carcasses of small ruminants with scrap car tyres. This study was therefore conducted to dete...
Typing of Foot and Mouth Disease Virus Circulating in Bangladesh by Reverse Transcription Polymerase Chain Reaction
Foot and Mouth Disease (FMD) is one of the highly contagious diseases of domestic and wild animals of many countries of the world including Bangladesh. The present study was undertaken to detect currently circulating FMD...
Prospective Study on Ano-Rectal Anomalies in Neonatal Farm Animals
The present study was carried out to clinically classify and assess the different conditions associated with ano-rectal anomalies in neonatal farm animals and to determine the outcome of surgically correction and surviva...
Third Degree Atrioventricular Block and Sudden Death Secondary to Chest Trauma in Crab-Eating Fox (Cerdocyon Thous, Linnaeus, 1758)
Third degree atrioventricular block in crab-eating fox was not related in the literature. Generally, it may occur secondary to several processes, including chest and cardiac trauma. This is a case report of third degree...