Sonneratinone: A new antimicrobial benzofuranone derivative from the endophytic fungus Aspergillus niger isolated from the mangrove plant Sonneratia apetala Buch.-Ham
Journal Title: Trends in Phytochemical Research - Year 2019, Vol 3, Issue 3
Abstract
A new antimicrobial benzofuranone derivative, named, sonneratinone (1), was isolated from the endophytic fungus Aspergillus niger, obtained from the leaves of Sonneratia apetala, a mangrove plant from the Sundarbans. Whilst the fungal strain was identified by macroscopic, microscopic and molecular techniques, the structure of the new compound was elucidated by spectroscopic means, e.g., 1D and 2D NMR, and HRESIMS. Sonneratinone (1) showed considerable antimicrobial activity against Micrococcus luteus, Staphylococcus aureus and Candida albicans in the resazurin 96-well microtitre plate antimicrobial assay.
Authors and Affiliations
Tauhidur Rahman Nurunnabi; Shaymaa Al-Majmaie; Lutfun Nahar; Ismini Nakouti; S. M. Mahbubur rahman; MD. Hossain Sohrab; MD. Morsaline Billah; Fyaz MD. Ismail; George P. Sharples; Satyajit D. Sarker
In-vitro alpha amylase and alpha glucosidase inhibitory potential of leaf hexane, ethyl acetate and methanol fractions of Pterocarpus soyauxii Taub
Diabetes mellitus is a critical clinical condition characterized by hyperglycemia in which an accelerated amount of glucose circulates in the blood plasma. This work attempts to evaluate the α-amylase and α-glucosidase i...
Evaluation of some medicinal plants for anti-tuberculosis activity from Adamawa state, Nigeria
Tuberculosis kills approximately two million people annually. This study aimed at evaluating some selected medicinal parts that are used traditionally in Adamawa State, to treat tuberculosis and related symptoms against...
A new lupane triterpene glycoside from Euphorbia boissierana Prokh.
Euphorbia plants displayed a wide range of biological activities including anticancer, antitumor, anti-diabetic, anticoagulant, antiproliferative, antioxidant, cytotoxic and modulation of multidrug resistance. Euphorbia...
Ameliorative nature of flavonoid naringin: A comprehensive review of antitoxic effects
Naringin is a flavonoid abundantly found in Citrus L. spp. with diverse applications. The present review emphasizes on the ameliorative role of naringin against hepatotoxicity, neurotoxicity, renal toxicity and cardiotox...
Chemical constituents from the leaves of Fraxinus excelsior L., Senna sulfurea (Collad.) H. S. Irwin et Barneby and Prosopis cineraria (L.) Druce
Fraxinus excelsior L. (Oleaceae) is used to treat diarrhoea, dysentery, jaundice, joint pain, malaria, sores, swelling and wounds. The leaves of Senna sulfurea (Collad.) H. S. Irwin et Barneby (Leguminosae) are effective...