Speciation and Antimicrobial Resistance Pattern of Acinetobacter Species From Clinical Isolates in Tertiary Care Hospital
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 6
Abstract
Introduction: Acinetobacter species are Gram negative non-fermentative bacteria. Previously these were considered just as an opportunistic pathogens, but recently have been emerged as an important nosocomial pathogen worldwide. In recent few years these have been involved in many outbreaks of hospital infections. Aims and Objectives: The present study was conducted to type the Acinetobacter isolates and to find the sensitivity and resistance pattern of Acinetobacter in our set up. Materials and Methods: The current study was conducted in our microbiology department, RIMS, Ranchi for a period of 1 year (January 2016 - December 2016). Different specimens were processed by standard methods and antibiotic sensitivity was performed by Kirby- Bauer disk diffusion technique as per Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: Out of a total 1890 culture positive specimens, 110 (5.8%) Acinetobacter isolates were obtained from various specimens. Speciations were done in which predominance of A. baumannii (84.5%) was seen followed by A.lwoffii (7.26%); A. haemolyticus (4.5%) and A. junnii (3.63%). High level of resistance were seen for Ampicillin (79.1%); Cefotaxime (78.1%); Ceftazidime (73%); Ceftriaxone (70.9%) and for urine samples Nalidixic acid (70%) and Norfloxacin (70%). Significant level of resistance were observed for Ciprofloxacin (63.64%), Levofloxacin (52.73%), Doxycycline (60%), Trimethoprim-sulfamethoxazole (60%); Gentamycin (54.55%). Sensitivity to Carbapenems was 70.9% and to both Amikacin and Piperacillin- tazobactam, 63.66% were found. Conclusion: In recent few years due to emergence of multidrug resistant strains of Acinetobacter, situation has become more problematic for the clinicians. So clinical co-relation must be undertaken to exclude commensal contaminant, before considering it to be a pathogen and prescribing appropriate antibiotic to the patient.
Authors and Affiliations
Ashok Kumar Sharma, Khushboo Kumari, Manoj Kumar, Amber Prasad
Keywords
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- EP ID EP533202
- DOI 10.21276/ijmrp.2018.4.6.029
- Views 87
- Downloads 0
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