Spectrophotometrically studied conditional stability constants and confirmation of complex formation of Cu (II), Cd (II) and Cr (III) complex with substituted thio- carbamidonaphthols
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 8
Abstract
Present work concern with spectrophotometrically investigation of conditional stability constant and formation constant of metal-ligand complexes of ligands 5-p-chlorophenyl thiocarbamido-1-nahthol with Cu(II), Cd(II) and Cr(III) metal ions with ethanol water systems at different proportions by Jobs method of continuous variation. The stiochiometry of complex formation found to be 1:1. This investigation helps to understand drug effect and drug activity of newly synthesized drugs.
Authors and Affiliations
Ajay Wadekar
A new approach to forced degradation studies using zolmitriptan tablets by a sensitive liquid chromatographic method
Forced degradation is a process that involves degradation of drug products and drug substances at conditions more severe than accelerated conditions and thus generates degradation products that can be studied to determin...
Herb Preparations Improve the Viability of Hippocampal Cells Suppressed by Amyloid Beta (1-42) Peptide
The aggregated amyloid peptides (Aβs) are considered as the hallmarks of Alzheimer's disease. We studied the ability of plant preparations, decreasing the aggregation state of amyloid peptides, to improve the viability o...
Quantitative analysis of α-glucosidase inhibitors by ECD with a column of the ion exchange resin of core-shell type filler
The α-glucosidase inhibitors, voglibose (VB), miglitol (MT), and acarbose (AB), are used as postprandial hyperglycemia inhibitors in the treatment of type 2 diabetes. The aim of this study was to develop a quantitative a...
Comparative clinical evaluation of Shriphaladi Yog & Kukshi Vasti in the management of irritable bowel syndrome
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder in which abdominal pain is associated with defecation or a change in bowel habit. Psychological and somatic management is also desirable in IBS due to...
Optimization of Microwave Assisted Extraction of Total Phenolic Contents from Triticum aestivum L. Whole-grain Cereal
Whole-grain cereals have unique blend of bioactive constituents and antioxidants which are proposed to be responsible for the health profits of whole-grain consumption. Nevertheless, phytochemicals and antioxidants in wh...