SPECTROSCOPIC STUDIES ON POUZOLZIA WIGHTII BENN
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2018, Vol 10, Issue 3
Abstract
Objective: The present study was aimed to reveal the spectroscopic profile (UV-Vis and FT-IR) of Pouzolzia wightii Benn. Methods: To detect the UV-Vis spectroscopic profile of P. wightii crude extracts were examined under UV-Vis Shimadzu spectrophotometer with the wavelength ranged from 100 to 1100 nm. About 1 mg of different extracts of petroleum ether, chloroform, ethyl acetate and acetone, ethanolic extracts of P. wightii were separately made into thin discs with 10-100 mg of potassium bromide using a mould and pressed under anhydrous conditions. The pellets were measured in an automatic recording FT-IR Spectrophotometer (Shimadzu 8400S) in the range of 400 to 4000 cm-1Results: In UV-Vis analysis, P. wightii petroleum ether extracts showed more number of peaks in roots (15) than other studied parts. Chloroform and ethyl acetate extracts of P. wightii leaves observed 9 peaks and acetone extracts of P. wightii stem showed 10 peaks. Medicinal property of plant extracts are confirmed by the presence of secondary metabolites. FT-IR analysis of ethyl acetate extracts of P. wightii leaves, stem and root observed the highest number of (16, 12 and 16) functional compounds.Conclusion: These UV-Vis and FT-IR spectroscopic results may be used as a pharmacognostic marker in the pharmaceutical industries and can be used as a chemometric tool to distinguish the studied P. wightii leaves, stem and root. The present study used to find out the bioactive compounds which may be subjected to subsequent target isolation. Further research will be needed for the structural characterization of the isolated compound by the use of different analytical methods such as NMR and mass spectrophotometer.
Authors and Affiliations
Syed Ali Fathima M. , Johnson M
Keywords
Related Articles
- EP ID EP567559
- DOI 10.22159/ijpps.2018v10i3.19336
- Views 82
- Downloads 0
RAPID, HIGHLY EFFICIENT AND STABILITY INDICATING RP-UPLC METHOD FOR THE QUANTITATIVE DETERMINATION OF POTENTIAL IMPURITIES OF CARVEDILOL ACTIVE PHARMACEUTICAL INGREDIENT
Objective: The main objective of the proposed study was to develop a sensitive, rapid and stability indicating reverse phase UV-UPLC method for the quantitative determination of potential impurities in carvedilol.Methods...
ASSESSMENT OF ANTIDIABETIC ACTIVITY OF THE TRADITIONAL INDIAN AYURVEDIC FORMULATION BRAHMI GRITHAM IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
Objective: The aim of the present study was to determine the antidiabetic activity of Brahmi gritham a traditional Indian ayurvedic formulation in streptozotocin-induced diabetes in rats.Methods: Diabetes was induced by...
DEVELOPMENT AND EVALUATION OF GASTRORETENTIVE FLOATING TABLETS OF A QUINAPRIL HCL BY DIRECT COMPRESSION TECHNIQUE
Objective: The present study was undertaken with an objective to design, develop and evaluate gastro retentive floating tablets of an antihypertensive drug, quinapril HCl, which release the drug in a sustained manner ove...
PROTECTIVE EFFECTS OF Α - CRYSTALLIN ON Β - AMYLOID (Aβ) INDUCED TOXICITY
Objectives: To investigate the protective role of α-crystallin against β-amyloid aggregation.Methods: In vitro spectroscopic methods and cell culture studies were done to validate our objective.Results: The molecular b...
POTENT BIOACTIVE METABOLITES OF CASUARINA JUNGHUHNIANA MIQ. ROOTS–A THERAPEUTIC APPROACH
Objective: Casuarina junghuhniana Miq. is a multipurpose tree, belongs to the family Casuarinaceae. It has a symbiotic association with actinomycete Frankia which makes the tree to grow vigorously on varied environmental...