Spectrum of Colorectal Cancers in a Tertiary Care Centre-A ClinicoPathological Correlation
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 2
Abstract
Introduction: Large intestine is affected by various types of lesions, both non-neoplastic and neoplastic. Due to vague symptoms, the clinical diagnosis is usually delayed. Colorectal cancer is the third leading cancer worldwide, accounting for approximately 9% of all cancers. A set of laboratory tests including biopsy is essential to arrive at a specific diagnosis for appropriate management. Aims and Objectives: The aim of this study is to find out the site wise distribution of colorectal tumours and to study the clinical profile and histopathology of various lesions. Materials and Methods: This two years study was done in Department of Pathology, Dr SCGMC Nanded from 2015-2017 which included biopsies and resected specimens of large intestine and Anal canal. All tissues were fixed in formalin, stained with H&E and special stains like Periodic Acid Schiff (PAS), Reticulin, Zeihl Neelsen (ZN) were done as and when required. Results: Out of 37 malignant lesions, 13 cases(35.0%) were Well differentiated Adenocarcinomas, 10 cases (27.1%)were Moderately differentiated Adenocarcinomas, 01 case (02.7%) was Poorly differentiated, 05 cases (13.6%) were Mucin secreting Adenocarcinomas and 01 case(02.7%) was Signet ring cell carcinoma. The most common histological grade in the present study was well differentiated Adenocarcinoma. Conclusion: Adenocarcinomas are the most common malignant lesions of colon in our study. As there is increasing incidence of malignancies early diagnosis by endoscopic biopsies in clinically suspicious patients is recommended for good management.
Authors and Affiliations
Dr P. S. Mulay
Keywords
Related Articles
- EP ID EP506078
- DOI -
- Views 67
- Downloads 0
Barium contrast evaluation of lower esophageal sphincter disorders with endoscopic correlation
Introduction: Lower esophageal sphincter disorders include achalasia cardia, hiatus hernia, peptic stricture, growth gastro-esophageal junction, schkatzki ring, and esophagitis. Barium swallow is an accurate method in th...
Histological Investigation Of Gingival Reaction To Direct Polymethyl Methacrylate Provisional Restorations
Purpose: This investigation evaluated the possible histological reactions to chairside fabricated methyl methacrylate provisional restorations depending on the time span. Materials and methods: Participants included 30 p...
Clinically detected Enteric Fever in Children – Blood Culture as a Diagnostic Aid
Enteric fever is considered a globally threatening disease in several developing countries, caused by the bacterium “Salmonella enterica serovar Typhi”. Taking diagnosis into concern, blood culture technique is the most...
Prevalence and Pattern of Macular Edema in Diabetes
Objective: Diabetic macular edema (DME) is the major cause of vision loss in patients with diabetic retinopathy (DR). The purpose of this study was to assess the prevalence of DME in pre diagnosed Type II diabetes mellit...
Pleomorphic Adenoma of the Sublingual Salivary Gland - A Rare Occurrence
Sublingual salivary gland tumours are very rare and most, that occur, are malignant. A case of pleomorphic adenoma of the sublingual salivary gland, presenting as a slow growing swelling in the floor of the mouth, is pre...