Spectrum of Histological Lesions in the Prostatic Specimens – A Two Year Study
Journal Title: Saudi Journal of Pathology and Microbiology - Year 2018, Vol 3, Issue 8
Abstract
Abstract:Prostate gland of male reproductive system is about the size of walnut and surrounds the urethra. With increasing life expectancy, increasing awareness and better health services, lesions of prostate has become a common specimen received for diagnostic of both benign and malignant lesions which may have a very similar presentation but their management and prognosis is quite different. Most important investigation is the biopsy of the prostate. A histopathological study of features of the lesion gives best diagnosis. Our objective of study is to evaluate the spectrum and correlation of prostatic lesions with presenting complaints of the patient. It was a combined cross-sectional study conducted in Pathology Departments of both Bhaskar Medical College and Satya Diagnostic Centre, Himayath Nagar during the period from November 2015 to October 2017. Specimens were taken through transurethral resection of prostate (TURP) and needle core biopsy (simple prostatectomy and radical prostatectomy). Data including name, age, department, symptoms and clinical diagnosis were noted. During the 2 year period, out of 105 specimens, incidence of benign lesions were 91.4% (96 cases) and malignant lesions were 8.6 % (9 cases) in the study. Benign lesions included Benign prostatic hyperplasia and malignant lesions included Prostatic adenocarcinoma. In benign lesions, maximum 41.7% (40 cases) were found in the age group of 61-70 years. The most common chief complaints in benign lesions were frequency 32.3% (31 cases), nocturia 20.9% (20 cases) and urgency 9.4 %(9 cases) followed by retention 7.3 % (7 cases), hesitancy 6.3%(6 cases) and poor stream 5.2%(5 cases). Among the malignant lesions, maximum 33.3% (3 cases) were seen in the age group 71-80 years with most common complaint of nocturia and hematuria in 22.2%(2 cases) followed by frequency, poor stream, intermittent stream, dribbling and retention constituting to 11.1% (1 case each). Benign and malignant prostatic lesions presents commonly in men more than 60 years of age. Frequency and nocturia were the common presenting symptoms in benign, whereas nocturia and hematuria were significantly associated with malignant lesions. Keywords: Frequency, nocturia, hematuria, BPH (Benign Prostatic Hypertrophy), Adenocarcinoma.
Authors and Affiliations
V Sailaja, Chai yaset, VVijay Sreedhar, P Shiva Ram
Keywords
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