SPERM COUNTS AND HORMONAL PROFILES OF ADULT MALES IN ABA METROPOLIS, SOUTH EAST NIGERIA
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2017, Vol 3, Issue 5
Abstract
Aim: This study aimed at providing baseline data on the fertility status and profile of male residents in Aba metropolis, South East Nigeria. Materials and Methods: One hundred and eighty-six men (186) between the ages of twenty-five to fifty years (25-50), comprising 84 fertile control, and 102 men diagnosed with infertility and attending infertility clinics in Aba metropolis were recruited into the study. The infertile subjects comprised of current smokers (26), those exposed to pesticides used in the control of pests and weeds in the farms and other pollutants (46) and bicycle riders (30). Semen samples were collected from the subjects after a minimum of 5 days abstinence from sexual intercourse. The percentage of motile spermatozoa, viable spermatozoa, sperm count and morphology of the spermatozoa were determined using standard WHO procedures. Follicle stimulating hormone, luteinizing hormone, testosterone and prolactin were analysed using enzyme linked immunosorbent assay kits. Analysis of variance (ANOVA) was used to compare mean differences among subgroups whilst student t-test was used to compare the differences between two groups. Values were considered significant at p<0.05. Results: The levels of FSH, LH, testosterone and sperm counts in the infertile subjects were significantly decreased (p<0.05) when compared with the levels in the fertile control subjects. Of the 102 diagnosed infertile males, (22.55%) of them were oligoospermic while (2.94%) were azoospermic. The levels of the pituitary hormones were significantly (p<0.05) increased in the oligospermic and azoospermic infertile males whereas the values were significantly reduced in the general subgroups of the infertile population. The sperm counts and testosterone level were, however, significantly reduced in both groups of the infertile males. Conclusion: This study showed significant decrease in gonadotrophins hormone (FSH, LH) in 74.51% and an increase in 25.49% but testosterone and sperm counts were low in all subgroups.
Authors and Affiliations
Ebirien-Agana S. Bartimaeus
Keywords
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