Squamous Metaplasia and Its Management in Non-malignant Bladder Diseases

Apply

Squamous Metaplasia and Its Management in Non-malignant Bladder Diseases

Journal Title: Üroonkoloji Bülteni - Year 2017, Vol 16, Issue 2

Abstract

Objective: To reveal possible associations between non-malignant bladder disease and malignancy by evaluating the pathologic examination results of patients who underwent cystectomy for non-malignant diseases and to suggest a point of view for disease management. Materials and Methods: Medical records of patients, who underwent cystectomy in our clinic between January 2005 and January 2015 for non-malignant diseases, were examined retrospectively. Results: A total of 14 patients were included in the study. The mean age of the patients was 58.7±9.3 years. Of the patients eight of them were followed up with interstitial cystitis (IC), five with neurogenic bladder and one with hemorrhagic cystitis. Time from diagnosis to cystectomy was 6.1±5.8 years on average in IC patients, 13.8±9.8 years in neurogenic bladder patients and 10 years in hemorrhagic cystitis patients. No malignancy finding was observed according to the pathologic examination results of the cystectomy specimens. However, either chronic or active inflammation was observed in all the patients. In addition to other pathologies non-keratinized squamous metaplasia was detected in five patients. Conclusion: Patients with non-malignant diseases should be followed-up with cystoscopy and bladder biopsy as a pre-malign lesion caution. Although cystectomy and urinary diversion are surgery methods with high complication rates, they could be suggested to well-informed patients as treatment alternatives.

Authors and Affiliations

Şenol Tonyalı, Hakan Bahadır Haberal, Mustafa Sertaç Yazıcı, Dilek Ertoy Baydar, Ali Ergen

Keywords

Evaluation of Role of Inflammatory Markers for the Prediction of Recurrence on Pathologic T1a Clear Cell Renal Cell Cancer Patients

Objective: To evaluate the role of neutrophil to lymphocyte ratio (NLR), high sensitive C-reactive protein (hs-CRP) and procalcitonin levels in the prediction of tumor recurrence in stage T1aN0M0 clear cell renal cell ca...

Tamsulosin Can Improve Lower Urinary Tract Symptoms in Patients Under Active Surveillance Due to Low Risk Prostate Cancer: Prospective Controlled Study

Objective: We aimed to evaluate the efficacy of tamsulosin in the treatment of lower urinary tract symptoms (LUTS) in patients under active surveillance (AS) for low-risk prostate cancer (Pca). Materials and Methods: Pat...

EP ID EP226691
DOI 10.4274/uob.818
Views 146
Downloads 0