Stereotactic electroencephalography-guided electrical stimulation-induced smile and laughter: a report of two cases
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 5
Abstract
The network of laughter/smile production and propagation in the brain is not yet fully understood. In this paper, we report two cases of medically refractory epilepsy patients with stereotactic EEG implantation, in which smiles (without pleasurable emotions and motor awareness) and laughter (with situationally incompatible pleasurable emotions) were repeatedly induced by electrical stimulation in the left precentral gyrus, and the right insular short gyrus, respectively. This phenomenon reflects the existence of distinct and linked emotional and behavioral networks for laughter.
Authors and Affiliations
Xinyi LIANG, Yanfeng XIE, Quanhong SHI, Yan ZHAN, Li JIANG, Wei. DAN
Construction of diagnostic model of depression in insomnia patients based on polysomnography data
[Objective] To establish a diagnostic model for depression in insomnia patients by mining polysomnography (PSG) data of insomnia patients with machine learning algorithms, and to provide a scientific basis for the diagno...
Progress of long chain non-coding RNAs in the inflammatory response to cerebral ischemia-reperfusion injury
Inflammatory response is one of the key mechanisms of cerebral ischemia/reperfusion injury (CIRI), which seriously affects the prognosis of patients. In recent years, it has been found that long non-coding RNA (LncRNA) i...
Clinical application of deep transcranial magnetic stimulation in mental disorders
Deep transcranial magnetic stimulation (dTMS) is a common form of physical therapy. In recent years, it has been increasingly used in the treatment of various mental diseases. Most research has focused on depressive diso...
The correlation between cognitive impairment and DNA methylation in the GRIN2B gene promoter region in bipolar depression patients with anxiety symptom
[Objective] To explore the correlation between cognitive function and methylation levels of various CpG sites in the promoter region of the glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B) gene in patients wit...
The application of virtual avatar in anorexia nervosa
Virtual avatar possesses unique advantages such as high degree of realism, immersion and visualization, and the research on applying it to the assessment and treatment of anorexia nervosa is increasing year by year. In t...