Stone Expulsion Rate of Small Distal Ureteric Calculus Could Be Predicted With Serum C-Reactive Protein, White Cell Counts And Neutrophil Percentage: A Prospective Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 11
Abstract
Purpose:To determine the relationship between stone expulsion rate of distal ureteric calculus less than or equal to 10mm in size and C reactive protein (CRP) level, white cell count and neutrophil percentage. Materials and Methods: A total of 143 patients with distal ureteric calculus of ≤10mm were evaluated for stoneexpulsion rate and its correlation with serum CRP, white cell count and neutrophil percentage. All patients received tablet Tamsulosin 0.4mg for 4 weeks or till the expulsion of stone. Patients were called weekly till 4 weeks, or early if there was history of stone expulsion.Patients were divided in two groups according to normal and elevated CRP levels, white cell count and neutrophil percentage at baseline for statistical analysis. Results: The patients had an average age of 35.6 ± 13.9 years. 52.4% were male. Ratio of right to left was 1.38:1. Majority of the patients with distal ureteric calculus ≤ 10mm passed their stone (78.3 %) with medical expulsion therapy. Expulsion of stone less than 5mm was statistically significant (p 0.013). Patients with normal neutrophil percentage and normal CRP level had higher stone expulsion rate than elevated neutrophil or CRP (96.6% vs. 48.1, 93.9% vs. 44.4% respectively). In patients with normal white cell count,89.7% passed their stone while in elevated white cell count group 44.4% passed their stone. Conclusion: In our study, patients with distal ureteric calculus of ≤10mmwith normal CRP level and normal neutrophil count had higher expulsion rate while WBC count showed no statistically significant association.
Authors and Affiliations
Kumar A, Agrawal C S, Sah S P, Joshi B R, Gupta M
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