Strontium - clinical and paraclinical aspects
Journal Title: Terapeutica, Farmacologie si Toxicologie Clinica - Year 2008, Vol 12, Issue 3
Abstract
[b]Introduction:[/b] Stable Strontium -meaning nonradioactive- is nontoxic, even when administered in large doses for prolonged periods. It also appears to be one of the most effective substances yet found for the prevention and treatment of osteoporosis and other bone-related conditions. Because of its chemical similarity to calcium, strontium can replace calcium to some extent in various biochemical processes in the body, including replacing a small proportion of the calcium in hydroxyapatite crystals of calcified tissues such as bones and teeth. Hemodialysis patients are at risk of developing trace element imbalances. [b]Material and method: [/b]In order to detect strontium in whole blood and dialyzed fluid, the authors developed a routine technique using one AAS Varian system SpectraAA-880 with GTA-100, PSD and Neslab CFT-33 refrigerated recirculator, dominick hunter hydrogen generator and Ar gas 99.999% Linde [b]Conclusion:[/b] Sr determination in the monitoring and diagnosis of Sr overload/deficiency and treatment follow-up might become important because Sr has a potential therapeutic value in the prevention and treatment of osteopenic disorder.
Authors and Affiliations
Gina Caragea, M. Ionică, R. Macovei
Keywords
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